Used 2021 GMC Sierra 2500HD for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- 4X2
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 9,171
- Stock #:
- I222201
- VIN:
- 1GT18LE7XNF222201
2022 GMC Sierra 2500HD
Pro Crew Cab RWD
9,171 mi
$39,201
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White
- Fuel type:
- Gasoline
- Interior color:
- Black (Charcoal)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 98,312
- VIN:
- 1GT29LE73LF269052
-$1,750
2020 GMC Sierra 2500HD
Base Double Cab LB 4WD
98,312 mi
$31,585
$29,835
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 43,602
- Stock #:
- 26FT757A
- VIN:
- 1GT49NE77NF162271
2022 GMC Sierra 2500HD
SLT Crew Cab 4WD
43,602 mi
$46,987
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 77,085
- Stock #:
- ZNF175936A
- VIN:
- 1GT49RE70NF175936
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
77,085 mi
$48,409
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White
- Fuel type:
- Biodiesel
- Transmission:
- Automatic
- Mileage:
- 108,123
- Stock #:
- H260996A
- VIN:
- 1GT49PEY9MF190513
2021 GMC Sierra 2500HD
AT4 Crew Cab 4WD
108,123 mi
$50,598
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 104,736
- Stock #:
- T103437A
- VIN:
- 1GT49REY6NF103437
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
104,736 mi
$47,799
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 67,176
- Stock #:
- 4254515
- VIN:
- 1GT49LE75MF254515
2021 GMC Sierra 2500HD
Base Crew Cab 4WD
67,176 mi
$37,706
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 42,992
- Stock #:
- U9121
- VIN:
- 1GT59LE79NF302300
2022 GMC Sierra 2500HD
Pro Double Cab 4WD
42,992 mi
$38,599
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 120,939
- Stock #:
- E35034A
- VIN:
- 1GT49NEY7NF136312
2022 GMC Sierra 2500HD
SLT Crew Cab 4WD
120,939 mi
$43,256
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 98,466
- Stock #:
- CT211600
- VIN:
- 1GT49ME72NF211600
-$2,100
2022 GMC Sierra 2500HD
SLE Crew Cab 4WD
98,466 mi
$39,916
$37,816
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 128,328
- Stock #:
- MF236652
- VIN:
- 1GT49REY8MF236652
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
128,328 mi
$47,794
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black (Ebony Twilight Metallic)
- Fuel type:
- Gasoline
- Interior color:
- Jet Black with Kalahari Accents
- Mileage:
- 91,984
- Stock #:
- GD03681A
- VIN:
- 1GT49PE77NF158930
-$1,978
2022 GMC Sierra 2500HD
AT4 Crew Cab 4WD
91,984 mi
$46,279
$44,301
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Summit White
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 100,250
- Stock #:
- 6GT9627A
- VIN:
- 1GT19LE78MF225075
2021 GMC Sierra 2500HD
Base Crew Cab 4WD
100,250 mi
$30,129
CarGurus Analysis:
2021 GMC Sierra 2500HD
With 1,693 currently listed for sale and an average price of $51,056.00, 30.8% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
78.4% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and comfort features, making it a strong contender in the heavy-duty truck market.
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Quicksilver Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 79,213
- Stock #:
- 24651B
- VIN:
- 1GT49LEY4LF246266
2020 GMC Sierra 2500HD
Base Crew Cab 4WD
79,213 mi
$39,695
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black With Kalahari Accents
- Transmission:
- Automatic
- Mileage:
- 123,975
- Stock #:
- C50240PA
- VIN:
- 1GT49PEY8MF239233
2021 GMC Sierra 2500HD
AT4 Crew Cab 4WD
123,975 mi
$47,048
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- White Frost Tricoat
- Fuel type:
- Biodiesel
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- Automatic
- Mileage:
- 139,541
- Stock #:
- 15463
- VIN:
- 1GT49REY8LF155813
-$3,119
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
139,541 mi
$44,469
$41,350
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Onyx Black
- Fuel type:
- Gasoline
- Interior color:
- Jet Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 42,095
- Stock #:
- T185353C
- VIN:
- 1GT19ME75MF190064
2021 GMC Sierra 2500HD
SLE Crew Cab 4WD
42,095 mi
$41,958
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black (Ebony Twilight Met)
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 88,215
- Stock #:
- NF359392
- VIN:
- 1GT49REY7NF359392
-$1,330
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
88,215 mi
$49,328
$47,998
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Gasoline
- Interior color:
- Gray (Dark Walnut/Dark Ash Grey)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 69,740
- Stock #:
- G320643A
- VIN:
- 1GT49RE71MF295436
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
69,740 mi
$53,871
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Summit White
- Fuel type:
- Biodiesel
- Interior color:
- Jet Black
- Transmission:
- Automatic
- Mileage:
- 140,277
- Stock #:
- G273507C
- VIN:
- 1GT49REY6LF100647
-$4,213
2020 GMC Sierra 2500HD
Denali Crew Cab 4WD
140,277 mi
$46,187
$41,974
- Year:
- 2021
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Pacific Blue Metallic
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 105,323
- Stock #:
- G25-896A-1
- VIN:
- 1GT49REY2MF115678
2021 GMC Sierra 2500HD
Denali Crew Cab 4WD
105,323 mi
$48,540
- Year:
- 2020
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 6.6L V8 Biodiesel
- Exterior color:
- Black
- Fuel type:
- Biodiesel
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 172,832
- Stock #:
- 9163
- VIN:
- 1GT19LEY6LF245543
2020 GMC Sierra 2500HD
Base Crew Cab 4WD
172,832 mi
$27,275
- Year:
- 2022
- Make:
- GMC
- Model:
- Sierra 2500HD
- Body type:
- Pickup Truck
- Doors:
- 4 doors
- Drivetrain:
- Four-Wheel Drive
- Engine:
- 401 hp 6.6L V8
- Exterior color:
- Black
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- 6-Speed Automatic
- Mileage:
- 108,367
- Stock #:
- 134933
- VIN:
- 1GT49RE79NF134933
2022 GMC Sierra 2500HD
Denali Crew Cab 4WD
108,367 mi
$48,220
CarGurus Analysis: 2021 GMC Sierra 2500HD
Summary
With 1,693 currently listed for sale and an average price of $51,056.00, 30.8% of 2021 GMC Sierra 2500HDs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 GMC Sierra 2500HD 5 / 5 stars.
78.4% of 2021 Sierra 2500HD models on CarGurus are accident free.
The 2021 GMC Sierra 2500HD is known for its upscale design and comfort features, making it a strong contender in the heavy-duty truck market.
Why it stands out
The 2021 GMC Sierra 2500HD distinguishes itself with its blend of rugged capability and upscale features, appealing to both work and leisure users. This heavy-duty pickup truck is equipped with advanced technology and comfort amenities that enhance the driving experience, setting it apart from competitors like the Ford F-150 and Ram 1500. The Sierra 2500HD offers a range of powerful engine options, including a robust Duramax diesel, which is known for its reliability and towing capacity. Additionally, the truck's spacious interior and high-quality materials reflect GMC's "Professional Grade" branding, making it a popular choice for those seeking both functionality and luxury. While it excels in many areas, potential buyers should be aware of some reported issues in earlier models, particularly concerning electrical systems and infotainment glitches.
Other model years to consider
- Average price: $75,065.00
- Good/great deal percentage: 33.0%
- User rating: 5 / 5
- Total listings: 3,984
- Average price: $68,857.00
- Good/great deal percentage: 33.3%
- User rating: 4 / 5
- Total listings: 4,051
- Average price: $49,344.00
- Good/great deal percentage: 29.7%
- User rating: 4.86 / 5
- Total listings: 1,130
This analysis is based on CarGurus' proprietary market data from July 20, 2026, CarGurus experts' opinions, and generative AI.
5.0 Overall rating
Filter by rating
Allan K
Reviewed a 2021 GMC Sierra 2500HD on Jan 18, 2021
-Excellent trailering mirrors with lights, allow increased visibility when backing up at night -Engine noise is relatively quiet compared to older diesel pick ups, can order at fast food drive throughs without shutting engine off -Fuel economy is good for a vehicle of this size (I have 3500HD, not 2500HD) -Driver safety features and various camera views are very helpful -Trim version for this review is Denali, with power running boards, really not missing anything significant
Anonymous
Reviewed a 2021 GMC Sierra 2500HD on Sep 3, 2022
An absolutely beautiful pickup ! Handles & rides exceptionally well !! Nobody will regret making the decision to purchase this awesome truck .
jordyn c
Reviewed a 2021 GMC AT4 Crew Cab 4WD on Dec 4, 2023
This car is not missing nothing at all it is perfect
Kevin K
Reviewed a 2021 GMC Sierra 2500HD on Apr 21, 2022
So far we are very happy.We appreciate the options and layout
2021 GMC Sierra 2500HD Trims
| Trim type | MSRP |
|---|---|
| LB RWD | $36,200 |
| Double Cab 4WD | $41,600 |
| SLE Double Cab 4WD | $46,400 |
| Base Crew Cab 4WD | $43,400 |
| SLE Crew Cab 4WD | $48,200 |
| SLT Crew Cab 4WD | $56,200 |
| AT4 Crew Cab 4WD | $59,100 |
| Denali Crew Cab 4WD | $65,500 |
2021 GMC Sierra 2500HD Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 GMC Sierra 2500HD prices has changed over time.
See more price trends2021 GMC Sierra 2500HD Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest Prices in Atlanta: The average price in Atlanta, GA ($57,364) is the highest among the listed cities, indicating strong demand in the region.
- Lowest Prices in 2014 Sierra: The average price in Philadelphia, PA ($45,620) is the lowest, suggesting a more price-sensitive market or higher inventory turnover.
- Inventory Levels Impact Pricing: Cities with higher inventory, such as Chicago (243 listings) and Dallas (235 listings), show relatively stable pricing around $53K, indicating a balanced supply-demand dynamic.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Atlanta, GA | 273 | $57,364 |
| Los Angeles, CA | 147 | $57,139 |
| Chicago, IL | 243 | $53,877 |
| Houston, TX | 229 | $55,829 |
| Miami, FL | 188 | $54,758 |
| New York, NY | 233 | $50,280 |
| Philadelphia, PA | 240 | $45,620 |
| Dallas, TX | 235 | $50,746 |
| Washington, DC | 243 | $53,181 |
| Boston, MA | 214 | $49,525 |
Pricing Analysis by Model Year
Key Insights
- Significant New-Car Premium: The 2026 GMC Sierra 2500HD is priced at $82,689, which is approximately 76.5% above its MSRP, indicating strong demand for the latest model.
- Depreciation Trends: The 2014 model shows the steepest depreciation, with an average price of $23,987, reflecting a -23.5% drop from its original MSRP.
- Best Value Years: The 2022 model is priced at $52,329, which is only -3.8% below its MSRP, making it a compelling option for buyers seeking recent models with minimal depreciation.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 GMC Sierra 2500HD | $47,000 | $82,689 | +76.5% |
| 2025 GMC Sierra 2500HD | $46,300 | $74,887 | +61.7% |
| 2024 GMC Sierra 2500HD | $45,400 | $68,411 | +50.6% |
| 2023 GMC Sierra 2500HD | $42,200 | $56,033 | +32.8% |
| 2022 GMC Sierra 2500HD | $36,200 | $52,329 | -3.8% |
| 2020 GMC Sierra 2500HD | $35,800 | $49,100 | +37.1% |
| 2019 GMC Sierra 2500HD | $38,200 | $39,859 | +4.3% |
| 2018 GMC Sierra 2500HD | $35,000 | $38,832 | +8.0% |
| 2017 GMC Sierra 2500HD | $34,190 | $36,278 | +6.1% |
| 2016 GMC Sierra 2500HD | $33,535 | $32,609 | -2.8% |
| 2015 GMC Sierra 2500HD | $33,195 | $29,567 | -11.1% |
| 2014 GMC Sierra 2500HD | $31,310 | $23,987 | -23.5% |
These recommendations are based on CarGurus' proprietary market data from July 16, 2026, CarGurus experts' opinions, and generative AI.
FAQs
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Relevant articles
2026 GMC Sierra 2500HD Pricing, Specs, and Release Date
Aside from a freshened color palette and broader availability of the trick MultiPro Tailgate, the 2026 GMC Sierra 2500HD full-size pickup truck soldiers on as a premium workhorse capable of towing up to 20,000 pounds in luxurious style.
2025 GMC Sierra 2500HD Pricing, Specs, and Release Date
Slotted between the light-duty 1500 and the ultra-tough 3500HD, the 2025 GMC Sierra 2500HD balances immense capability with the comfort and latest amenities expected from today's truck buyers. Upgrades for 2025 include a newly standard trailer brake controller.
Who Makes GMC Cars?
GMC is an American automaker that builds premium trucks and SUVs with capability and comfort as selling points. GMC is a division of General Motors and all of its vehicles share platforms with other GM products. Certain products, like its trucks, are very closely related to Chevrolet products.
