Used 2021 Lexus IS for SaleNationwide
473 vehicles found
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 135,892
- Stock #:
- A263056
- VIN:
- JTHC81F28M5044064
2021 Lexus IS
300 AWD
135,892 mi
$22,706
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White Pearl
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 72,594
- Stock #:
- X112888
- VIN:
- JTHAA1D22M5112888
2021 Lexus IS
300 RWD
72,594 mi
$29,891
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 29,576
- Stock #:
- PN5055280
- VIN:
- JTHGZ1B26N5055280
2022 Lexus IS
350 F Sport RWD
29,576 mi
$41,510
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 47,476
- Stock #:
- T3827A
- VIN:
- JTHGZ1B23L5035937
2020 Lexus IS
350 RWD
47,476 mi
$32,463
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Glazed Caramel
- Transmission:
- 8-Speed Automatic
- Mileage:
- 71,382
- Stock #:
- K3770
- VIN:
- JTHAA1D26M5111355
-$1,000
2021 Lexus IS
300 RWD
71,382 mi
$26,104
$25,104
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Iridium
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 123,362
- Stock #:
- M5110031P
- VIN:
- JTHCA1D27M5110031
2021 Lexus IS
300 RWD
123,362 mi
$24,169
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 63,161
- Stock #:
- 044240
- VIN:
- JTHGZ1B27M5044240
2021 Lexus IS
350 F Sport RWD
63,161 mi
$36,694
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 16,609
- Stock #:
- N5056138
- VIN:
- JTHGZ1B28N5056138
2022 Lexus IS
350 F Sport RWD
16,609 mi
$44,292
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 46,051
- Stock #:
- H17402A
- VIN:
- JTHDA1D27L5107147
2020 Lexus IS
300 RWD
46,051 mi
$28,805
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Red
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 25,706
- Stock #:
- S020789A
- VIN:
- JTHGZ1B23M5043599
2021 Lexus IS
350 F Sport RWD
25,706 mi
$39,486
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- White w/Black Geometric Trim
- Transmission:
- Automatic
- Mileage:
- 64,886
- Stock #:
- N5056859
- VIN:
- JTHGZ1B20N5056859
2022 Lexus IS
350 F Sport RWD
64,886 mi
$37,999
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red
- Transmission:
- 6-Speed Automatic
- Mileage:
- 65,058
- Stock #:
- PDM0834
- VIN:
- JTHGZ1E28L5018319
2020 Lexus IS
350 AWD
65,058 mi
$32,546
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Mileage:
- 73,012
- Stock #:
- L5106890
- VIN:
- JTHAA1D25L5106890
2020 Lexus IS
300 RWD
73,012 mi
$25,214
CarGurus Analysis:
2021 Lexus IS
With 483 currently listed for sale and an average price of $35,785.00, 31.1% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
72.7% of 2021 Lexus IS models on CarGurus are accident free.
The 2021 Lexus IS enters its fourth generation, featuring a sporty design, various engine options, and enhanced handling, making it appealing to both luxury and performance-oriented buyers.
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Rioja Red W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 55,285
- Stock #:
- 80802A
- VIN:
- JTHDA1D29N5119352
2022 Lexus IS
300 RWD
55,285 mi
$31,431
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 46,905
- Stock #:
- I365239B
- VIN:
- JTHGZ1B23M5047362
2021 Lexus IS
350 F Sport RWD
46,905 mi
$36,483
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 45,726
- Stock #:
- L19337T
- VIN:
- JTHD81F25L5041528
-$1,662
2020 Lexus IS
300 AWD
45,726 mi
$29,820
$28,158
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 47,186
- Stock #:
- 2031813A
- VIN:
- JTHD81F20N5049118
2022 Lexus IS
300 AWD
47,186 mi
$34,083
- Year:
- 2020
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray (Liquid Platinum)
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Dual Clutch
- Mileage:
- 94,534
- Stock #:
- 5103668
- VIN:
- JTHAA1D20L5103668
2020 Lexus IS
300 RWD
94,534 mi
$23,649
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 241 hp 2L I4
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 63,738
- Stock #:
- N5121210
- VIN:
- JTHAA1D26N5121210
2022 Lexus IS
300 RWD
63,738 mi
$29,427
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 260 hp 3.5L V6
- Exterior color:
- Iridium
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 6-Speed Automatic
- Mileage:
- 40,247
- Stock #:
- 2P45747
- VIN:
- JTHC81F28M5045747
2021 Lexus IS
300 AWD
40,247 mi
$33,925
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Flare Red w/Ginsumi
- Transmission:
- Automatic
- Mileage:
- 64,298
- Stock #:
- N55960A
- VIN:
- JTHGZ1E22M5018401
2021 Lexus IS
350 F Sport AWD
64,298 mi
$38,590
- Year:
- 2022
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 22,893
- Stock #:
- A16355A
- VIN:
- JTHGZ1B27N5050749
-$1,580
2022 Lexus IS
350 F Sport RWD
22,893 mi
$44,579
$42,999
- Year:
- 2021
- Make:
- Lexus
- Model:
- IS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 311 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black W/Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 31,166
- Stock #:
- KHP5984
- VIN:
- JTHGZ1B22M5039690
2021 Lexus IS
350 F Sport RWD
31,166 mi
$36,789
CarGurus Analysis: 2021 Lexus IS
overall
Summary
With 483 currently listed for sale and an average price of $35,785.00, 31.1% of 2021 Lexus IS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus IS 4.62 / 5 stars.
72.7% of 2021 Lexus IS models on CarGurus are accident free.
The 2021 Lexus IS enters its fourth generation, featuring a sporty design, various engine options, and enhanced handling, making it appealing to both luxury and performance-oriented buyers.
Why it stands out
The 2021 Lexus IS distinguishes itself in the compact luxury sports sedan market by combining sporty aesthetics with impressive performance capabilities. With multiple powertrain options, including a 2.0-liter turbocharged inline-four and a 3.5-liter V6, the IS offers versatility that can cater to various driver preferences. The "Lexus Driving Signature" philosophy enhances the driving experience through seamless performance, allowing for precise handling that appeals to driving enthusiasts. Owners commend its stylish design and luxurious interior, which feature high-quality materials and a comfortable layout, although some have noted the absence of modern tech features like real-time GPS and wireless Apple CarPlay. Overall, the 2021 IS balances sportiness with luxury, providing a solid alternative to its German competitors while maintaining Lexus' renowned reputation for reliability.
Other model years to consider
- Average price: $44,124.00
- Good/great deal percentage: 36.3%
- Total listings: 1,368
- Average price: $42,121.00
- Good/great deal percentage: 34.3%
- User rating: 4.8 / 5
- Total listings: 1,229
- Average price: $38,390.00
- Good/great deal percentage: 32.8%
- User rating: 5 / 5
- Total listings: 981
This analysis is based on CarGurus' proprietary market data from June 29, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
Amy N
Reviewed a 2021 Lexus IS on Aug 14, 2021
Great car, stylish, good value, sporty, and gorgeous to look at. I love the safety and security features. Remote start and speed settings in the app are great features. Missing- GPS tracking in real-time would be great like Tesla vehicles.
Anonymous
Reviewed a 2021 Lexus IS on Feb 11, 2023
This really has a sporty feel. The AWD, 3.5 Liter V6 is definitely the way to go on this vehicle. The Apple Car Play is incredible and makes the GPS option unnecessary. The gauge cluster looks modern and easy to use. The 360 degree cameras are also a great option. The exterior look of this car is beautiful. I have the matador red which is metallic red with the black 19” wheel rims. Very stylish. A very nice riding car.
Robert O
Reviewed a 2021 Lexus IS on Jan 15, 2024
Great car. Luxury , economy, and style. Rides smooth & fast. Mechanically reliable. Lexus is the best!
Jason M
Reviewed a 2021 Lexus IS on Apr 21, 2023
Im a bit partial because mine has every option available. The premium sound package is worth every penny. I hear its bad on gas. I have the AWD V6 which is plenty fast, so I drive it in eco full time. I get 100 miles on 15 dollars of gas @ 3.30 a gallon. Thats bad? Brakes in this car are amazing. They work along with the computer downshifting on hills perfectly. Anyone who has driven a standard before will notice it too. Its just great stock ecu tuning. Not to mention the brakes act in unison with the AWD. The car does not move in the snow (in a good way). Meaning there is no slipping, sliding or the car trying to get traction. It just goes. Also, thanks to the amazing braking system, there is also no real type of sliding when slowing down or stopping. I live in New England, so my car has seen weather of all types. Bad weather is a non factor. With all that being said, I also have snow tires. Which doesnt hurt and helps tremendously. Fun fact, the snow mode also works great during heavy rain.. just a fyi. Lets see. Its quiet, comfortable and the touch screen is perfect. The body lines are also spot on. There is ZERO wind noise. It looks like it spent a lot of time wind tunnel tested. I personally love the lines of the car and the daytime running lights are the best.. hands down. The back Robocop style taillight has been copied by many. The subtle red on the leds nail it. Not to mention the subtilties of just light things. A lot of attention to detail. Lexus listened to its consumers and said we hear you and well work on that. Which, honestly, you have to appreciate. Great car.. Thank you Lexus.
2021 Lexus IS Trims
| Trim type | MSRP |
|---|---|
| 350 F Sport AWD | $44,950 |
| 350 F Sport RWD | $42,950 |
| 300 AWD | $41,050 |
| 300 RWD | $39,050 |
2021 Lexus IS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus IS prices has changed over time.
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