Used 2021 Lexus RX 350 F SPORT Handling AWD for SaleNationwide
31 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- CIRCUIT RED
- Transmission:
- Automatic
- Mileage:
- 35,024
- Stock #:
- 36505B
- VIN:
- 2T2YZMDA3MC265487
2021 Lexus RX
350 F SPORT Handling AWD
35,024 mi
Sarasota, FL
Fair Deal
$40,622
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 71,345
- Stock #:
- I143325O
- VIN:
- 2T2YZMDA1MC278447
2021 Lexus RX
350 F SPORT Handling AWD
71,345 mi
Lake City, FL
Great Deal
$30,698
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 79,633
- Stock #:
- PM2836
- VIN:
- 2T2YZMDA1MC284765
2021 Lexus RX
350 F SPORT Handling AWD
79,633 mi
Merrillville, IN
Good Deal
$34,235
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 103,906
- Stock #:
- XH15596A
- VIN:
- 2T2YZMDA1MC260773
Price drop
-$1,006
2021 Lexus RX
350 F SPORT Handling AWD
103,906 mi
Charleston, SC
Good Deal
$32,798
$31,792
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 86,736
- Stock #:
- RP548
- VIN:
- 2T2YZMDAXMC261453
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
86,736 mi
Ephrata, PA
Fair Deal
$35,480
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 78,665
- Stock #:
- H26918A
- VIN:
- 2T2YZMDA5MC272053
2021 Lexus RX
350 F SPORT Handling AWD
78,665 mi
Wichita, KS
Fair Deal
$37,689
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 80,161
- Stock #:
- L265223A
- VIN:
- 2T2YZMDA5MC296997
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
80,161 mi
Reno, NV
Fair Deal
$35,090
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 63,213
- Stock #:
- 26183302
- VIN:
- 2T2YZMDA3MC302862
2021 Lexus RX
350 F SPORT Handling AWD
63,213 mi
North Miami, FL
Fair Deal
$38,924
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 59,920
- Stock #:
- 274129
- VIN:
- 2T2YZMDA0MC274129
2021 Lexus RX
350 F SPORT Handling AWD
59,920 mi
Snead, AL
Fair Deal
$39,416
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Mica
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,730
- Stock #:
- 72F11506
- VIN:
- 2T2YZMDAXMC307878
2021 Lexus RX
350 F SPORT Handling AWD
45,730 mi
Gilroy, CA
Fair Deal
$41,023
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 47,463
- Stock #:
- MC280087
- VIN:
- 2T2YZMDA7MC280087
2021 Lexus RX
350 F SPORT Handling AWD
47,463 mi
Dayton, OH
Fair Deal
$40,948
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,452
- Stock #:
- B3268817
- VIN:
- 2T2YZMDA2MC268817
2021 Lexus RX
350 F SPORT Handling AWD
45,452 mi
Tomball, TX
Good Deal
$40,975
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 60,529
- Stock #:
- BX24291
- VIN:
- 2T2YZMDA8MC280891
2021 Lexus RX
350 F SPORT Handling AWD
60,529 mi
Brooklyn, NY
Fair Deal
$35,995
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 67,339
- Stock #:
- PU633
- VIN:
- 2T2YZMDA3MC289188
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
67,339 mi
Dunn, NC
Fair Deal
$37,899
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 60,767
- Stock #:
- P79153
- VIN:
- 2T2YZMDA4MC271086
2021 Lexus RX
350 F SPORT Handling AWD
60,767 mi
Bellflower, CA
Fair Deal
$36,617
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 106,170
- Stock #:
- ZC281029
- VIN:
- 2T2YZMDA9MC281029
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
106,170 mi
San Antonio, TX
Fair Deal
$33,282
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 44,993
- Stock #:
- 28506066
- VIN:
- 2T2YZMDA9MC276218
Price drop
-$1,000
2021 Lexus RX
350 F SPORT Handling AWD
44,993 mi
Greensboro, NC
Good Deal
$40,998
$39,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 73,138
- Stock #:
- M1351
- VIN:
- 2T2YZMDA5MC264504
Photos coming soon
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
73,138 mi
Henderson, NV
Fair Deal
$36,995
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 54,018
- Stock #:
- 28233370
- VIN:
- 2T2YZMDA0MC270954
2021 Lexus RX
350 F SPORT Handling AWD
54,018 mi
O Fallon, IL
Fair Deal
$41,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Blue
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 58,922
- Stock #:
- 3017
- VIN:
- 2T2YZMDAXMC280407
2021 Lexus RX
350 F SPORT Handling AWD
58,922 mi
Auburn, WA
Good Deal
$37,495
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 54,319
- Stock #:
- 70312197
- VIN:
- 2T2YZMDA6MC294529
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
54,319 mi
Henderson, NV
Fair Deal
$40,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- Automatic
- Mileage:
- 108,534
- Stock #:
- 29247974
- VIN:
- 2T2YZMDA9MC262965
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
108,534 mi
Charlotte, NC
Fair Deal
$31,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 52,413
- Stock #:
- G45330B
- VIN:
- 2T2YZMDA3MC277543
New arrival
2021 Lexus RX
350 F SPORT Handling AWD
52,413 mi
Salt Lake City, UT
No Rating
No Price Listed
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black (Obsidian)
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,155
- Stock #:
- 17UY0185
- VIN:
- 2T2YZMDA2MC305557
2021 Lexus RX
350 F SPORT Handling AWD
46,155 mi
Ogden, UT
No Rating
$37,674
FAQs
How much does the Lexus RX 350 F SPORT Handling AWD cost?
The average Lexus RX 350 F SPORT Handling AWD costs about $34,808.13. The average price has decreased by -3.7% since last year. The 432 for sale on CarGurus range from $29,573 to $64,817 in price.
How many Lexus RX 350 F SPORT Handling AWD vehicles have no reported accidents or damage?
357 out of 432 for sale have no reported accidents or damage.
What is the fuel economy of the Lexus RX 350 F SPORT Handling AWD?
Depending on the engine and options, the Lexus RX 350 F SPORT Handling AWD gets between 22 and 24 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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