Used 2021 Lexus RX Hybrid for Sale nearRochester, NY
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,552
- Stock #:
- 080563
- VIN:
- 2T2YGMDA0NC080563
2022 Lexus RX Hybrid
450h F Sport Handling AWD
51,552 mi
$44,421
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 59,670
- Stock #:
- 28318032
- VIN:
- 2T2HGMDA8LC043807
2020 Lexus RX Hybrid
450h AWD
59,670 mi
$36,297
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 44,949
- Stock #:
- 3024206
- VIN:
- 2T2JGMDA5NC081001
2022 Lexus RX Hybrid
450h AWD
44,949 mi
$45,478
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Green
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 21,751
- Stock #:
- 27983507
- VIN:
- 2T2HGMDA1LC047133
2020 Lexus RX Hybrid
450h AWD
21,751 mi
$44,397
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nebula Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- 6-Speed CVT
- Mileage:
- 47,033
- Stock #:
- 6544
- VIN:
- 2T2HGMDA2MC063648
2021 Lexus RX Hybrid
450h AWD
47,033 mi
$42,672
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 64,397
- Stock #:
- 70103040
- VIN:
- 2T2AGMDA0LC047335
2020 Lexus RX Hybrid
450h AWD
64,397 mi
$37,997
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 29,024
- Stock #:
- 70106062
- VIN:
- 2T2YGMDA8MC064304
-$1,000
2021 Lexus RX Hybrid
450h F Sport Handling AWD
29,024 mi
$47,997
$46,997
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Blue
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 41,440
- Stock #:
- 70056156
- VIN:
- 2T2HGMDA5NC089596
2022 Lexus RX Hybrid
450h AWD
41,440 mi
$46,497
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 60,247
- Stock #:
- 28816547
- VIN:
- 2T2HGMDA4MC064039
2021 Lexus RX Hybrid
450h AWD
60,247 mi
$40,997
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Red
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 81,577
- Stock #:
- 70052879
- VIN:
- 2T2JGMDA9LC055286
2020 Lexus RX Hybrid
450h AWD
81,577 mi
$34,747
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 13,529
- Stock #:
- 28312799
- VIN:
- 2T2HGMDA2NC090303
2022 Lexus RX Hybrid
450h AWD
13,529 mi
$51,997
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 90,477
- Stock #:
- 70121083
- VIN:
- 2T2YGMDA5NC072555
2022 Lexus RX Hybrid
450h F Sport Handling AWD
90,477 mi
$39,497
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 42,879
- Stock #:
- 70183457
- VIN:
- 2T2HGMDA5NC076895
2022 Lexus RX Hybrid
450h AWD
42,879 mi
$47,997
CarGurus Analysis:
2021 Lexus RX Hybrid
With 223 currently listed for sale and an average price of $40,286.00, 34.1% of 2021 Lexus RX Hybrids for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
73.5% of 2021 RX Hybrid models on CarGurus are accident free.
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (Beige)
- Transmission:
- 6-Speed CVT
- Mileage:
- 60,684
- Stock #:
- 6642
- VIN:
- 2T2HGMDA0LC056602
2020 Lexus RX Hybrid
450h AWD
60,684 mi
$40,372
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 52,876
- Stock #:
- B100290
- VIN:
- 2T2JGMDA7MC058043
2021 Lexus RX Hybrid
450h AWD
52,876 mi
$43,210
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 41,931
- Stock #:
- MC057524
- VIN:
- 2T2HGMDA9MC057524
2021 Lexus RX Hybrid
450h AWD
41,931 mi
$45,086
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Brown (TAN)
- Transmission:
- Automatic
- Mileage:
- 72,468
- Stock #:
- Y6364
- VIN:
- JTJJGKFA2N2021596
2022 Lexus RX Hybrid
450hL Luxury AWD
72,468 mi
$44,893
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 54,795
- Stock #:
- 1LT2145
- VIN:
- 2T2JGMDA2MC062145
2021 Lexus RX Hybrid
450h AWD
54,795 mi
$43,107
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 98,241
- Stock #:
- A17948
- VIN:
- JTJJGKFA5L2014042
2020 Lexus RX Hybrid
450hL Luxury AWD
98,241 mi
$35,861
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 85,968
- Stock #:
- 075802
- VIN:
- 2T2HGMDA0NC075802
2022 Lexus RX Hybrid
450h AWD
85,968 mi
$41,504
CarGurus Analysis: 2021 Lexus RX Hybrid
Summary
With 223 currently listed for sale and an average price of $40,286.00, 34.1% of 2021 Lexus RX Hybrids for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
73.5% of 2021 RX Hybrid models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX Hybrid stands out as a luxury crossover that blends comfort, efficiency, and a long-running reputation for reliability. Lexus has been a pioneer in premium hybrid technology, and the RX Hybrid line has carried that identity for years. For buyers, that means a vehicle aimed at delivering a quiet, comfortable ride and a well-crafted interior while still returning strong fuel economy.
For 2021, the RX Hybrid benefited from the third-generation updates that included Apple CarPlay and Android Auto, along with a wireless charging pad that arrived that year. The model also used Lexus’ infotainment setup with a trackpad and touchscreen interface for the 12.3-inch screen, which was described as more intuitive than before. Standard and available safety equipment remained a major part of the appeal, and the RX Hybrid’s mix of premium materials, technology, and efficiency makes it attractive to shoppers who want a refined daily driver.
There are tradeoffs, though. The RX Hybrid is not as fast or fun to drive as some rivals, and older Lexus infotainment systems have a reputation for being less intuitive. It can also be expensive on the used market, but for many buyers the combination of comfort, fuel efficiency, and Lexus durability is exactly what makes the 2021 RX Hybrid distinctive.
Other model years to consider
- Average price: $57,028.00
- Good/great deal percentage: 33.0%
- User rating: 5 / 5
- Total listings: 803
- Average price: $36,695.00
- Good/great deal percentage: 35.2%
- User rating: 5 / 5
- Total listings: 196
- Average price: $27,764.00
- Good/great deal percentage: 33.8%
- User rating: 5 / 5
- Total listings: 154
This analysis is based on CarGurus' proprietary market data from August 10, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Anonymous
Reviewed a 2021 Lexus RX Hybrid on Mar 11, 2021
Smooth, comfortable, reliable, full of amenities, beautiful! Puts a smile on my face every morning!
Antonio B
Reviewed a 2021 Lexus RX Hybrid on Jun 9, 2021
Overall The RX 450 h is very powerful ,smooth driving, excellent control, Very stylish and offers you the luxury of the Lexus brand.
B M
Reviewed a 2021 Lexus 450h F Sport Handling AWD on Mar 10, 2024
Great mileage with pretty good size SUV. 3 years of use and close to 100,000 miles with no issues whatsoever . This is a keeper
2021 Lexus RX Hybrid Trims
| Trim type | MSRP |
|---|---|
| 450hL AWD | $51,310 |
| 450h F Sport Handling AWD | $53,720 |
| 450hL Luxury AWD | $57,310 |
| 450h F Sport AWD | $51,400 |
| 450h AWD | $47,920 |
2021 Lexus RX Hybrid Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX Hybrid prices has changed over time.
See more price trendsFAQs
How much does the 2021 Lexus RX Hybrid cost in Rochester, NY?
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What fuel types are available?
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