Used 2021 Lexus RX Hybrid for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 77,692
- Stock #:
- T260310A
- VIN:
- JTJHGKFA9N2027538
-$2,500
2022 Lexus RX Hybrid
450hL AWD
77,692 mi
$37,598
$35,098
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black w/Scored Aluminum Trim
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,729
- Stock #:
- U6453
- VIN:
- 2T2YGMDA0LC050847
2020 Lexus RX Hybrid
450h F Sport Performance AWD
74,729 mi
$38,314
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 69,908
- Stock #:
- 3606
- VIN:
- 2T2SGMDA6LC046226
2020 Lexus RX Hybrid
450h F Sport AWD
69,908 mi
$34,995
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Green Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Glazed Caramel
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 37,833
- Stock #:
- D10423A
- VIN:
- 2T2HGMDA0MC072039
2021 Lexus RX Hybrid
450h AWD
37,833 mi
$43,894
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 74,813
- Stock #:
- GU1026
- VIN:
- 2T2HGMDA3MC063626
2021 Lexus RX Hybrid
450h AWD
74,813 mi
$36,163
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Ultra White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 56,732
- Stock #:
- T04239L
- VIN:
- 2T2YGMDA7LC044074
2020 Lexus RX Hybrid
450h F Sport Performance AWD
56,732 mi
$39,995
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black w/Matte Walnut Trim
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 29,261
- Stock #:
- VP3368A
- VIN:
- 2T2HGMDA3NC090052
2022 Lexus RX Hybrid
450h AWD
29,261 mi
$41,585
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- White (Parchment)
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 29,560
- Stock #:
- G2757A
- VIN:
- 2T2JGMDA2NC091498
2022 Lexus RX Hybrid
450h AWD
29,560 mi
$47,582
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 73,004
- Stock #:
- 26NC073341
- VIN:
- 2T2HGMDA2NC073341
2022 Lexus RX Hybrid
450h AWD
73,004 mi
$38,294
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Red
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 53,167
- Stock #:
- 9998
- VIN:
- 2T2YGMDA8LC045492
2020 Lexus RX Hybrid
450h F Sport Performance AWD
53,167 mi
$42,299
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 47,453
- Stock #:
- M666146A
- VIN:
- 2T2HGMDAXMC071061
2021 Lexus RX Hybrid
450h AWD
47,453 mi
$41,197
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Matador Red Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 50,341
- Stock #:
- PDN7368
- VIN:
- 2T2HGMDA5LC043540
2020 Lexus RX Hybrid
450h AWD
50,341 mi
$38,453
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 51,030
- Stock #:
- 260439B
- VIN:
- 2T2HGMDA9MC065798
-$1,962
2021 Lexus RX Hybrid
450h AWD
51,030 mi
$43,427
$41,465
CarGurus Analysis:
2021 Lexus RX Hybrid
With 223 currently listed for sale and an average price of $40,286.00, 34.1% of 2021 Lexus RX Hybrids for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
73.5% of 2021 RX Hybrid models on CarGurus are accident free.
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 37,699
- Stock #:
- 28773251
- VIN:
- 2T2HGMDA4MC057673
-$1,000
2021 Lexus RX Hybrid
450h AWD
37,699 mi
$41,998
$40,998
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 51,927
- Stock #:
- LC053237
- VIN:
- 2T2HGMDAXLC053237
2020 Lexus RX Hybrid
450h AWD
51,927 mi
$37,635
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 50,528
- Stock #:
- CTBTLC048130
- VIN:
- 2T2SGMDA3LC048130
2020 Lexus RX Hybrid
450h F Sport AWD
50,528 mi
$40,594
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 29 MPG
- Fuel type:
- Hybrid
- Interior color:
- Glazed Caramel
- Transmission:
- Automatic
- Mileage:
- 38,732
- Stock #:
- D67882
- VIN:
- JTJHGKFA4M2018678
2021 Lexus RX Hybrid
450hL AWD
38,732 mi
$45,549
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Glazed Caramel
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 24,490
- Stock #:
- L26241A
- VIN:
- 2T2JGMDA2NC077052
2022 Lexus RX Hybrid
450h AWD
24,490 mi
$44,715
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Circuit Red
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 70,801
- Stock #:
- U5430
- VIN:
- 2T2YGMDA9MC060942
2021 Lexus RX Hybrid
450h F Sport Handling AWD
70,801 mi
$38,684
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 19,819
- Stock #:
- OW26453
- VIN:
- 2T2YGMDA8NC089043
2022 Lexus RX Hybrid
450h F Sport Handling AWD
19,819 mi
$45,574
- Year:
- 2020
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 20,895
- Stock #:
- 22EM0072P
- VIN:
- 2T2JGMDA0LC056679
2020 Lexus RX Hybrid
450h AWD
20,895 mi
$43,149
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- Black (Caviar)
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Birch
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 26,851
- Stock #:
- ATD012793A
- VIN:
- 2T2JGMDA2NC084874
2022 Lexus RX Hybrid
450h AWD
26,851 mi
$48,173
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX Hybrid
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 3.5L V6 Hybrid
- Exterior color:
- White
- Combined gas mileage:
- 30 MPG
- Fuel type:
- Hybrid
- Interior color:
- Black
- Transmission:
- Continuously Variable Transmission
- Mileage:
- 73,619
- Stock #:
- L7N058044
- VIN:
- 2T2YGMDA0MC058044
2021 Lexus RX Hybrid
450h F Sport Handling AWD
73,619 mi
$38,467
CarGurus Analysis: 2021 Lexus RX Hybrid
Summary
With 223 currently listed for sale and an average price of $40,286.00, 34.1% of 2021 Lexus RX Hybrids for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Lexus RX Hybrid 4.67 / 5 stars.
73.5% of 2021 RX Hybrid models on CarGurus are accident free.
Why it stands out
The 2021 Lexus RX Hybrid stands out as a luxury crossover that blends comfort, efficiency, and a long-running reputation for reliability. Lexus has been a pioneer in premium hybrid technology, and the RX Hybrid line has carried that identity for years. For buyers, that means a vehicle aimed at delivering a quiet, comfortable ride and a well-crafted interior while still returning strong fuel economy.
For 2021, the RX Hybrid benefited from the third-generation updates that included Apple CarPlay and Android Auto, along with a wireless charging pad that arrived that year. The model also used Lexus’ infotainment setup with a trackpad and touchscreen interface for the 12.3-inch screen, which was described as more intuitive than before. Standard and available safety equipment remained a major part of the appeal, and the RX Hybrid’s mix of premium materials, technology, and efficiency makes it attractive to shoppers who want a refined daily driver.
There are tradeoffs, though. The RX Hybrid is not as fast or fun to drive as some rivals, and older Lexus infotainment systems have a reputation for being less intuitive. It can also be expensive on the used market, but for many buyers the combination of comfort, fuel efficiency, and Lexus durability is exactly what makes the 2021 RX Hybrid distinctive.
Other model years to consider
- Average price: $57,028.00
- Good/great deal percentage: 33.0%
- User rating: 5 / 5
- Total listings: 803
- Average price: $36,695.00
- Good/great deal percentage: 35.2%
- User rating: 5 / 5
- Total listings: 196
- Average price: $27,764.00
- Good/great deal percentage: 33.8%
- User rating: 5 / 5
- Total listings: 154
This analysis is based on CarGurus' proprietary market data from August 10, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
David D
Reviewed a 2021 Lexus 450h AWD on Aug 25, 2025
I think it’s the most enjoyable car I’ve ever driven in my 66 years of driving
Anonymous
Reviewed a 2021 Lexus RX Hybrid on Mar 11, 2021
Smooth, comfortable, reliable, full of amenities, beautiful! Puts a smile on my face every morning!
Antonio B
Reviewed a 2021 Lexus RX Hybrid on Jun 9, 2021
Overall The RX 450 h is very powerful ,smooth driving, excellent control, Very stylish and offers you the luxury of the Lexus brand.
B M
Reviewed a 2021 Lexus 450h F Sport Handling AWD on Mar 10, 2024
Great mileage with pretty good size SUV. 3 years of use and close to 100,000 miles with no issues whatsoever . This is a keeper
2021 Lexus RX Hybrid Trims
| Trim type | MSRP |
|---|---|
| 450hL AWD | $51,310 |
| 450h F Sport Handling AWD | $53,720 |
| 450hL Luxury AWD | $57,310 |
| 450h F Sport AWD | $51,400 |
| 450h AWD | $47,920 |
2021 Lexus RX Hybrid Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Lexus RX Hybrid prices has changed over time.
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