Used 2021 Mercedes-Benz CLS for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 85,757
- Stock #:
- A-743
- VIN:
- W1K2J5JB7MA090983

2021 Mercedes-Benz CLS
450 RWD
85,757 mi
$30,145
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Iridium Silver Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 96,397
- Stock #:
- LA048249
- VIN:
- WDD2J5JB2LA048249

2020 Mercedes-Benz CLS
450 Coupe RWD
96,397 mi
$26,338
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Grey)
- Transmission:
- Automatic
- Mileage:
- 56,932
- Stock #:
- 26298B
- VIN:
- W1K2J5KB4LA071028

2020 Mercedes-Benz CLS
450 Coupe 4MATIC
56,932 mi
$31,167
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 66,053
- Stock #:
- LA050264A
- VIN:
- WDD2J5KBXLA050264

2020 Mercedes-Benz CLS
450 Coupe 4MATIC
66,053 mi
$29,270
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- designo Diamond White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (designo Macchiato Beige/Titian Red)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,372
- Stock #:
- N086829
- VIN:
- W1K2J5KB1MA086829

2021 Mercedes-Benz CLS
450 4MATIC
36,372 mi
$37,761
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 52,785
- Stock #:
- LA073863
- VIN:
- W1K2J5JB2LA073863

2020 Mercedes-Benz CLS
450 Coupe RWD
52,785 mi
$35,148
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,415
- Stock #:
- A103866T
- VIN:
- W1K2J5KB4NA103866

2022 Mercedes-Benz CLS
450 4MATIC
43,415 mi
$38,619
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,658
- Stock #:
- PC6165
- VIN:
- W1K2J5KB9LA074748

2020 Mercedes-Benz CLS
450 Coupe 4MATIC
49,658 mi
$29,686
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (designo MANUFAKTUR Graphite Metallic)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 49,710
- Stock #:
- 095079
- VIN:
- W1K2J5KB7MA095079

2021 Mercedes-Benz CLS
450 4MATIC
49,710 mi
$36,885
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 40,102
- Stock #:
- SNA106175
- VIN:
- W1K2J5KB3NA106175

2022 Mercedes-Benz CLS
450 4MATIC
40,102 mi
$40,518
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Yacht Blue/Black
- Transmission:
- Automatic
- Mileage:
- 28,919
- Stock #:
- BA286159A
- VIN:
- W1K2J5JB5MA093316

-$1,000
2021 Mercedes-Benz CLS
450 RWD
28,919 mi
$43,081
$42,081
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Magma Gray/Macchiato Beige
- Transmission:
- 9-Speed Automatic
- Mileage:
- 22,268
- Stock #:
- 099928CM1
- VIN:
- W1K2J5KB0NA099928

2022 Mercedes-Benz CLS
450 4MATIC
22,268 mi
$40,999
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (designo Selenite Grey Magno)
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Magma Grey/Espresso Brown)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 33,916
- Stock #:
- 048695
- VIN:
- WDD2J5JB3LA048695

2020 Mercedes-Benz CLS
450 Coupe RWD
33,916 mi
$35,299
About 2021 Mercedes-Benz CLS
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Blue
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Marsala Brown/Espresso Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,095
- Stock #:
- 26K-5460A
- VIN:
- WDD2J5KB7LA052327

2020 Mercedes-Benz CLS
450 Coupe 4MATIC
39,095 mi
$40,490
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (designo Selenite Grey Magno)
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 106,315
- Stock #:
- 077679
- VIN:
- W1K2J5KB9LA077679

2020 Mercedes-Benz CLS
450 Coupe 4MATIC
106,315 mi
$22,200
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Classic Red/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,186
- Stock #:
- SU35942T
- VIN:
- W1K2J5KB4NA098944

2022 Mercedes-Benz CLS
450 4MATIC
50,186 mi
$39,125
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,158
- Stock #:
- 260826B-1
- VIN:
- W1K2J5JB9LA075741

2020 Mercedes-Benz CLS
450 Coupe RWD
58,158 mi
$34,999
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray
- Transmission:
- Automatic
- Mileage:
- 68,746
- Stock #:
- CCJTLA050650
- VIN:
- WDD2J6BB7LA050650

2020 Mercedes-Benz CLS
AMG CLS 53 Coupe 4MATIC
68,746 mi
$37,492
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 63,838
- Stock #:
- KN049190
- VIN:
- WDD2J5JB0LA049190

2020 Mercedes-Benz CLS
450 Coupe RWD
63,838 mi
$31,794
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- Rear-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 27 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,657
- Stock #:
- 074781
- VIN:
- W1K2J5JB5LA074781

-$964
2020 Mercedes-Benz CLS
450 Coupe RWD
58,657 mi
$32,957
$31,993
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray ([992] Selenite Grey Metallic)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 3,118
- VIN:
- W1K2J5KB1MA091836
![Gray ([992] Selenite Grey Metallic) 2021 Mercedes-Benz CLS Coupe All-Wheel Drive Automatic](https://static.cargurus.com/images/forsale/2026/01/13/00/58/2021_mercedes-benz_cls-pic-832979311599051558-1024x768.jpeg?io=true&width=640&height=480&fit=bounds&format=jpg&auto=webp)
2021 Mercedes-Benz CLS
450 4MATIC
3,118 mi
$37,950
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 429 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Bengal Red/Black
- Transmission:
- Automatic
- Mileage:
- 52,530
- Stock #:
- P13784A
- VIN:
- WDD2J6BB3LA049687

2020 Mercedes-Benz CLS
AMG CLS 53 Coupe 4MATIC
52,530 mi
$38,847
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- CLS
- Body type:
- Coupe
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray
- Combined gas mileage:
- 26 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 17,267
- Stock #:
- 10728Q
- VIN:
- W1K2J5KB3NA106144

-$2,000
2022 Mercedes-Benz CLS
450 4MATIC
17,267 mi
$50,170
$48,170
Overview

The Mercedes-Benz CLS-Class is a large luxury car with coupe-like styling. It was last redesigned for the 2019 model year and gets updated tech features for 2021. It competes with cars like the Audi A7 and Genesis G90.
The CLS-Class is a big four-door car, though it’s graceful and elegant thanks to its low stance, sleek roofline, and blacked-out B-pillar for the the-oh-so-popular coupe-like profile. The wide grille and angled headlights make the front end look a little more sporty than you might expect based on the side view, and because it’s a Mercedes, the various wheel designs are gorgeous.
There are two CLS models, the CLS 450 and the AMG CLS 53, both carrying over unchanged this year. The CLS 450 features an inline-six engine rated for 362 horsepower and 369 pound-feet of torque, a nine-speed automatic transmission, and a mild-hybrid electrical system. Rear-wheel drive (RWD) is standard and Mercedes’ 4MATIC all-wheel drive (AWD) system is available. The AMG model is tuned for 429 hp and 384 lb-ft, and also features a (performance-enhanced) nine-speed transmission and AWD. With the base CLS, you’ll get 24 mpg city, 31 highway, and 26 combined, or 23/26/30 with AWD. The AMG CLS 53 is rated for 21/27/23.
The CLS seats five on leather upholstery and includes features like keyless entry, push-button start, and 64-color ambient lighting. The AMG model adds upgraded upholstery and a sport steering wheel. Options across the lineup include heated and cooled seats, massaging seats, and three-zone automatic climate control.
For 2021, the CLS gets an updated infotainment system in the form of the Mercedes-Benz User Experience (MBUX) system. A 12.3-inch display pairs with a new 12.3-inch digital gauge cluster for all functions, and Apple CarPlay and Android Auto are also included. The adaptive cruise control system now incorporates live traffic data—another nice touch. Buyers have the choice of two Burmester audio systems.
Standard safety features include blind-spot monitoring, forward-collision warning, automatic emergency braking, and driver-attention monitoring. For 2021, the automatic emergency braking system responds to oncoming traffic.
The lovely CLS-Class remains an enticing choice, and the updated tech features help it stay competitive.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Mercedes-Benz CLS Trims
| Trim type | MSRP |
|---|---|
| AMG CLS 53 4MATIC | $81,550 |
| 450 RWD | $70,300 |
| 450 4MATIC | $72,800 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2021 Mercedes-Benz CLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz CLS prices has changed over time.
See more price trends2021 Mercedes-Benz CLS Pricing Analysis
Pricing by Popular US Cities
Market Area: Nationwide
Key Insights
- Highest-Price Market: Miami, FL leads with an average price of $39,150, indicating a premium market for the CLS.
- Best Value: Houston, TX offers the lowest average price at $29,995, presenting a more affordable option for buyers.
- Inventory Drives Stability: New York, NY has the most listings at 35, suggesting a robust market presence that may stabilize pricing.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| New York, NY | 35 | $37,595 |
| Washington, DC | 28 | $37,647 |
| Philadelphia, PA | 27 | $31,990 |
| Los Angeles, CA | 26 | $38,446 |
| Houston, TX | 24 | $29,995 |
| Miami, FL | 23 | $39,150 |
Pricing by Trim Packages
Key Insights
- Volume Leader: The 450 4MATIC trim has the highest inventory with 183 listings, indicating strong demand for this configuration.
- Premium Spread: The AMG CLS 53 4MATIC trim, priced at $81,550, represents a significant premium over the other trims, highlighting the luxury segment's appeal.
- Drivetrain Effect: All trims feature different drivetrains, with the AWD option generally commanding higher prices, as seen with the 450 4MATIC.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 183 | $72,800 | AWD | 3.0L 362 hp I6 |
| 450 RWD | 67 | $70,300 | RWD | 3.0L 362 hp I6 |
| AMG CLS 53 4MATIC | 2 | $81,550 | AWD | 3.0L 429 hp I6 |
Pricing Analysis by Model Year
Key Insights
- New-Car Premium: The 2023 model year shows a starting MSRP of $76,500, with an average price of $53,158, reflecting a 30.5% depreciation.
- Depreciation Curve: The steepest depreciation is observed in the 2013 model year, with a decline of 78.3%, indicating significant value loss over time.
- Best Value Sweet Spot: The 2018 model year offers a balance with an average price of $28,433, making it an attractive option for budget-conscious buyers.
Model Year Pricing
| Model Year | Starting MSRP | Avg Price | Avg Price vs Starting MSRP |
|---|---|---|---|
| 2023 | $76,500 | $53,158 | -30.5% |
| 2022 | $72,950 | $48,026 | -34.2% |
| 2021 | $70,300 | $39,819 | -43.4% |
| 2020 | $69,950 | $34,349 | -50.9% |
| 2019 | $69,200 | $31,788 | -54.1% |
| 2018 | $75,150 | $28,433 | -62.2% |
| 2017 | $67,550 | $31,519 | -53.3% |
| 2016 | $66,900 | $22,318 | -66.6% |
| 2015 | $65,990 | $21,510 | -67.4% |
| 2014 | $72,100 | $16,218 | -77.5% |
| 2013 | $72,000 | $15,651 | -78.3% |
| 2012 | $71,300 | $17,917 | -74.9% |
These recommendations are based on CarGurus' proprietary market data from September 30, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
Is the 2021 Mercedes-Benz CLS a good car?
The 2021 Mercedes-Benz CLS sits in a moderate market position, which makes it a reasonable option if you want a luxury sedan with some shopping flexibility. The current market also shows 36.4% of listings as good or great deals, which gives you a useful starting point when comparing individual cars.
What should I look for when buying a used 2021 Mercedes-Benz CLS?
Accident-free inventory is solid at 77.7% — always verify the vehicle history report.
You should prioritize a history report first, then focus your inspection on condition, maintenance records, and any signs of prior damage or inconsistent repairs. Because the clean-inventory share is strong but not universal, it pays to compare examples carefully and avoid paying a premium for a car with incomplete documentation or visible wear.
Is now a good time to buy a used 2021 Mercedes-Benz CLS?
This looks like a moderate, selective buyer’s market, so you have room to shop carefully rather than rush into the first example you see.
- Deal availability: 36.4% of listings are priced as good or great deals.
- Inventory: There are 121 listings available.
- Clean inventory: 77.7% of listings are accident-free.
That mix suggests you can find value if you compare condition and pricing closely. If you want the best odds of landing a strong example, focus on well-documented cars and use the deal share as a filter rather than a guarantee.
Should I buy a 2021 Mercedes-Benz CLS or consider a different year?
If you're weighing the 2021 against nearby model years, here's how to think about it:
Choose the 2021 if:
- 36.4% of listings are priced as good or great deals.
- Accident-free inventory is solid at 77.7% — always verify the vehicle history report.
The bottom line: The 2021 is the better path if you want a current-year option with a decent share of attractive listings and a healthy pool of accident-free cars. If you’re especially price-sensitive, it can still make sense to compare nearby years and choose the one with the best combination of condition, history, and asking price.
These recommendations are based on CarGurus' proprietary market data from September 29, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
