Used 2021 Mercedes-Benz GLS for SaleNationwide
869 vehicles found
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 49,063
- Stock #:
- 26327A
- VIN:
- 4JGFF5KE8NA613169

-$1,000
2022 Mercedes-Benz GLS
450 4MATIC
49,063 mi
$47,649
$46,649
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Macchiato/Magmagray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 119,106
- Stock #:
- F30131
- VIN:
- 4JGFF5KE2LA097968

2020 Mercedes-Benz GLS
450 4MATIC
119,106 mi
$24,715
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 43,900
- Stock #:
- MA575387
- VIN:
- 4JGFF8KE2MA575387

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
43,900 mi
$67,175
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,934
- Stock #:
- UL703900
- VIN:
- 4JGFF5KE5NA703900

2022 Mercedes-Benz GLS
450 4MATIC
48,934 mi
$46,939
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 61,213
- Stock #:
- RW391346A
- VIN:
- 4JGFF5KE2LA220636

2020 Mercedes-Benz GLS
450 4MATIC
61,213 mi
$35,089
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- MANUFAKTUR Diamond White Bright
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 97,420
- Stock #:
- 35T02002
- VIN:
- 4JGFF5KE6NA625790

-$1,000
2022 Mercedes-Benz GLS
450 4MATIC
97,420 mi
$32,984
$31,984
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 72,785
- Stock #:
- CMBTLA212930
- VIN:
- 4JGFF5KE6LA212930

2020 Mercedes-Benz GLS
450 4MATIC
72,785 mi
$31,792
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 82,501
- Stock #:
- A655836
- VIN:
- 4JGFF5KE0NA655836

2022 Mercedes-Benz GLS
450 4MATIC
82,501 mi
$36,010
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 69,395
- Stock #:
- QX1241A
- VIN:
- 4JGFF5KE3LA138463

2020 Mercedes-Benz GLS
450 4MATIC
69,395 mi
$34,379
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,848
- Stock #:
- 9432HU
- VIN:
- 4JGFF5KE2NA755842

2022 Mercedes-Benz GLS
450 4MATIC
23,848 mi
$51,292
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 80,363
- Stock #:
- CC260152A
- VIN:
- 4JGFF5KE3MA442104

2021 Mercedes-Benz GLS
450 4MATIC
80,363 mi
$33,698
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 62,365
- Stock #:
- U13249A
- VIN:
- 4JGFF5KE9MA329693

-$3,267
2021 Mercedes-Benz GLS
450 4MATIC
62,365 mi
$39,677
$36,410
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- Automatic
- Mileage:
- 58,453
- Stock #:
- 17260A
- VIN:
- 4JGFF5KE5NA618667

2022 Mercedes-Benz GLS
450 4MATIC
58,453 mi
$43,497
CarGurus Analysis:
2021 Mercedes-Benz GLS
With 888 currently listed for sale and an average price of $49,656.00, 37.4% of 2021 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.67 / 5 stars.
83.1% of 2021 GLS models on CarGurus are accident free.
The 2021 Mercedes-Benz GLS boasts a spacious interior with three rows of seating, luxurious features, and impressive technology, appealing to buyers looking for a full-size luxury SUV.
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 97,593
- Stock #:
- 5MC6037
- VIN:
- 4JGFF5KE8LA157073

2020 Mercedes-Benz GLS
450 4MATIC
97,593 mi
$27,850
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 67,675
- Stock #:
- XPF8455A
- VIN:
- 4JGFF8KE4MA315850

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
67,675 mi
$58,799
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 109,498
- Stock #:
- TA368435A
- VIN:
- 4JGFF5KE9LA120212

2020 Mercedes-Benz GLS
450 4MATIC
109,498 mi
$26,639
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 550 hp 4L V8
- Exterior color:
- Diamond White Metallic
- Combined gas mileage:
- 17 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 32,491
- Stock #:
- M7144
- VIN:
- 4JGFF8HB9MA407484

2021 Mercedes-Benz GLS
600 Mercedes-Maybach 4MATIC
32,491 mi
$98,994
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black Leather
- Transmission:
- 9-Speed Automatic
- Mileage:
- 33,261
- Stock #:
- 29234
- VIN:
- 4JGFF5KE5NA747556

2022 Mercedes-Benz GLS
450 4MATIC
33,261 mi
$51,084
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- Automatic
- Mileage:
- 72,378
- Stock #:
- 26-281
- VIN:
- 4JGFF5KE8LA273843

2020 Mercedes-Benz GLS
450 4MATIC
72,378 mi
$34,893
- Year:
- 2020
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- designo Diamond White Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 63,233
- Stock #:
- G63147B
- VIN:
- 4JGFF5KE1LA117899

-$910
2020 Mercedes-Benz GLS
450 4MATIC
63,233 mi
$34,284
$33,374
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 55,795
- Stock #:
- NA691094
- VIN:
- 4JGFF5KE8NA691094

2022 Mercedes-Benz GLS
450 4MATIC
55,795 mi
$42,999
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Polar White
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 69,728
- Stock #:
- A401980T
- VIN:
- 4JGFF8GE8MA401980

2021 Mercedes-Benz GLS
580 4MATIC
69,728 mi
$41,913
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 50,473
- Stock #:
- L25241A
- VIN:
- 4JGFF8KE0MA302710

-$1,403
2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
50,473 mi
$63,698
$62,295
CarGurus Analysis: 2021 Mercedes-Benz GLS
overall

Summary
With 888 currently listed for sale and an average price of $49,656.00, 37.4% of 2021 Mercedes-Benz GLS models for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2021 Mercedes-Benz GLS 4.67 / 5 stars.
83.1% of 2021 GLS models on CarGurus are accident free.
The 2021 Mercedes-Benz GLS boasts a spacious interior with three rows of seating, luxurious features, and impressive technology, appealing to buyers looking for a full-size luxury SUV.
Why it stands out
The 2021 Mercedes-Benz GLS is often regarded as the S-Class of SUVs, offering a remarkable blend of luxury and performance. This full-size SUV comes equipped with three rows of spacious seating, emphasizing comfort for all occupants, making it suitable for families or those who frequently transport multiple passengers. The GLS is powered by various engine options, including a robust twin-turbocharged V8, delivering not only impressive power but also a seamless and engaging driving experience. Its tech-savvy interior features the new MBUX infotainment system, a massive touch screen, and advanced driver assistance systems, which enhance both usability and safety. Although the GLS excels in many areas, potential buyers should note the cramped third row and the vehicle's relatively poor fuel economy, especially in the more powerful AMG variant.
Other model years to consider
- Average price: $75,871.00
- Good/great deal percentage: 37.3%
- User rating: 5 / 5
- Total listings: 1,447
- Average price: $81,825.00
- Good/great deal percentage: 37.1%
- Total listings: 1,487
- Average price: $34,464.00
- Good/great deal percentage: 36.8%
- User rating: 5 / 5
- Total listings: 797
This analysis is based on CarGurus' proprietary market data from June 29, 2026, CarGurus experts' opinions, and generative AI.
4.7 Overall rating
Filter by rating
Wilber R
Reviewed a 2021 Mercedes-Benz GLS on Sep 4, 2024
Excellent car, very good finish full of attributes, spacious.
James C
Reviewed a 2021 Mercedes-Benz GLS on Dec 22, 2022
I feel that the features listed for this vehicle is good. I just didnt see one option that would have made me buy the vehicle fast. I did not see the multi contour massage feature. I wished that it would have been made clear on the listing.
Michelle A
Reviewed a 2021 Mercedes-Benz 450 4MATIC on Apr 8, 2023
Very nice ride, drives so well and well built. I love it so far!!
2021 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 450 4MATIC | $76,000 |
| AMG GLS 63 4MATIC AWD | $132,100 |
| 580 4MATIC | $98,850 |
| 600 Mercedes-Maybach 4MATIC | $160,500 |
2021 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2021 Mercedes-Benz GLS prices has changed over time.
See more price trendsFAQs
How much does the 2021 Mercedes-Benz GLS cost?
Is the 2021 Mercedes-Benz GLS a good car?
How many 2021 Mercedes-Benz GLS vehicles have no reported accidents or damage?
Is the 2021 Mercedes-Benz GLS safe?
What is the fuel economy of the 2021 Mercedes-Benz GLS?
What fuel types are available?
Relevant articles

The Best Large SUVs for Gas Mileage in 2026
Large SUVs and great gas mileage don't tend to go hand-in-hand. That said, some models are more impressive than others. Here are our favourites, including the BMW X7 and Chevrolet Tahoe.

The Best New Cars for Old Money Style in 2026
Whether you’re looking for something classic and timeless or you just want a nice vehicle that doesn’t project extreme affluence, there are a lot of new vehicles on the market today that feel luxurious, look elegant, yet don’t attract much attention.

Mercedes-Benz GLS Buying Guide: Cost, Reliability, and the Best Years to Buy
Discover the ultimate buying guide for purchasing a used Mercedes-Benz GLS covering each generation since 2017. Whether you're a first-time buyer or a Mercedes enthusiast, this comprehensive overview will help you research your next pre-owned Mercedes-Benz GLS.