Used 2021 Toyota Sequoia for SaleNationwide

How much does the 2021 Toyota Sequoia cost?

Prices are up 1.94% year-over-year — a sign of continued demand for this model year.

There are 149 listings available, which suggests a relatively limited pool of used Sequoias to shop from.

Is the 2021 Toyota Sequoia a good car?

Generally — the 2021 Toyota Sequoia earns a 4.4/5 user rating and a 7/10 expert rating. The standout strength is Form and function at 9/10.

Owners consistently point to practicality, good looks, reliable performance, a smooth ride, and ample features. That lines up with the Sequoia’s use case as a roomy, truck-like SUV for you if you value utility and everyday usability over a more carlike feel. The main trade-offs are its poor fuel economy and poor value for money, and the age of the design still shows in the cabin and overall execution. Even so, the market signal is decent: 35.6% of listings are priced as good or great deals.

Is the 2021 Toyota Sequoia reliable?

Owners rate it 4.4/5, a solid signal of long-term satisfaction.

Owner feedback highlights reliable performance, and the model’s age is also tied to a reputation for good reliability and dependability. The expert review also points to the Sequoia’s long-running, proven hardware as part of its appeal, which can matter if you want something you can count on over time. Toyota also emphasizes the simplicity of the system and the durability that comes from a long production run. For used buyers, the main long-term ownership risk is that age-related wear can still show up, so condition matters more than mileage alone.

What should I look for when buying a used 2021 Toyota Sequoia?

At 67.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.

You should start with a vehicle history report and then prioritize a pre-purchase inspection, especially on higher-mileage examples or trucks with incomplete service records. Focus on overall condition, signs of prior bodywork, and whether the truck-like chassis and suspension feel tight and well maintained. Because the Sequoia is an older design, you’ll want to pay close attention to how well the cabin, electronics, and mechanical components have aged.

Key things to evaluate:

• Trim level: The SR5 includes 18-inch alloy wheels, LED fog lights, three-zone climate control, pushbutton start, remote keyless entry, a 7-inch touchscreen, a power moonroof, and a power-adjustable driver’s seat. The SR5 Premium Package adds a power-folding/reclining third row, power-adjustable front passenger seat, leather upholstery, and heated front seats. The TRD Sport adds unique 20-inch wheels, chrome accents, Satin-black TRD logos, TRD floor mats, Bilstein shocks, and a TRD sport-tuned suspension. The Limited adds leather upholstery, heated front seats, auto-dimming chrome-clad power side mirrors with integrated turn signals, a power liftgate, navigation, and a 12-speaker premium audio system. The Nightshade Edition adds black 20-inch wheels, black leather upholstery, second-row captain’s chairs, and LED fog lights with dark chrome surrounds. The TRD Pro adds LED fog lights from Rigid Industries, 18-inch BBS forged aluminum TRD wheels, Fox Racing shocks, a TRD-tuned suspension, beefed-up skid plates, and a limited-slip center differential. The Platinum adds heated-and-ventilated front seats, heated second-row captains chairs, a larger 9-inch touchscreen, a power-adjustable steering wheel, and an air suspension.
• Powertrain: Every trim uses a 5.7-liter V8 with 381 horsepower and 401 pound-feet of torque, paired with a six-speed automatic. Rear-wheel drive is standard, and four-wheel drive is available with low range. It delivers stout acceleration and truck-like driving manners, but the six-speed setup and heavy weight work against fuel economy.
• Safety package: Toyota Safety Sense-P includes forward-collision warning, automatic emergency braking, pedestrian detection, adaptive cruise control, lane-departure warning, and automatic high beams. It also comes standard with blind-spot monitoring, rear cross-traffic alert, and front-and-rear parking sensors. There are no optional safety features, but you do not get lane-keeping assist or lane-tracing assist.
• Infotainment: The standard system uses a 7-inch touchscreen with Apple CarPlay, Android Auto, Amazon Alexa, and a WiFi hotspot. A larger 9-inch screen is available on higher-spec examples, and the system is easy to use thanks to simple menus and physical buttons.
• Fuel efficiency: The rear-wheel-drive version returns 13 mpg city, 17 mpg highway, and 15 mpg combined. The four-wheel-drive version has the same city and highway figures and returns 14 mpg combined. Either way, you should expect full-size truck fuel economy.

Which 2021 Toyota Sequoia trim should I buy?

The 2021 Toyota Sequoia is offered in 6 trim levels: SR5, TRD Sport, Limited, Nightshade Edition, TRD Pro, and Platinum.

Here's the short version:

• SR5: This is the entry point, but it still gives you the core Sequoia experience with the V8, the 7-inch touchscreen, and a solid list of standard comfort and convenience features. If you want the lowest-cost way into the model, this is the trim to start with.
• TRD Sport: This trim adds distinctive styling, Bilstein shocks, and a TRD sport-tuned suspension, so it’s the one to consider if you want a more individualized look and a slightly firmer setup.
• Limited: This is the best-value trim for many shoppers because it layers in leather, heated front seats, navigation, a power liftgate, and a premium audio system without jumping all the way to the top end.
• Nightshade Edition: This is the style-focused choice, with blacked-out exterior details, black leather, and second-row captain’s chairs. It makes sense if appearance and a more upscale vibe matter to you.
• TRD Pro: This is the off-road-oriented trim, with skid plates, Fox Racing shocks, a TRD-tuned suspension, and a limited-slip center differential. Choose it if you want the most rugged setup in the lineup.
• Platinum: This is the most luxurious version, adding heated-and-ventilated front seats, heated second-row captain’s chairs, a larger touchscreen, a power-adjustable steering wheel, and air suspension.

Toyota Safety Sense-P is standard across the lineup, and there are no optional safety features.

Is now a good time to buy a used 2021 Toyota Sequoia?

This is a moderate market for selective buyers, so you should shop carefully and move quickly when you find a strong example.

• Deal availability: 35.6% of listings are priced as good or great deals.
• Inventory: There are 149 listings available.
• Price trend: Prices are up 1.94% year-over-year.
• Clean inventory: 67.8% of listings are accident-free.

If you find a listing below $47,344, that's toward the low end of the year-round range and worth acting on quickly.

What is the 2021 Toyota Sequoia's resale value?

The current average of $48,763 sits slightly above last year's $47,837.

That upward move suggests the Sequoia has held demand reasonably well, even with its age and fuel-economy drawbacks. For a future seller, that means you may not be dealing with a steep depreciation curve if you buy well and keep the truck in good condition. The limited supply also helps support pricing, especially for cleaner examples with desirable equipment.

Vehicles with solid owner satisfaction ratings, like this model year's 4.4/5, tend to retain buyer demand, which supports resale value over time.

Is the 2021 Toyota Sequoia safe?

The 2021 Toyota Sequoia earns four-star ratings in the NHTSA rollover test.

It earns a 5/10 safety score from our experts.

Toyota Safety Sense-P is standard, and it includes forward-collision warning, automatic emergency braking, pedestrian detection, adaptive cruise control, lane-departure warning, and automatic high beams. You also get blind-spot monitoring, rear cross-traffic alert, and front-and-rear parking sensors. There are no optional safety features, but you do not get lane-keeping assist or lane-tracing assist. The main caveat is that the Sequoia rides on an older platform, and its crash-test coverage is limited.

Should I buy a 2021 Toyota Sequoia or consider a different year?

If you're weighing the 2021 against nearby model years, here's how to think about it:

Choose the 2021 if:

• 35.6% of listings are priced as good or great deals.
• At 67.8% accident-free, a meaningful share of listings has prior incidents — history verification is especially important.
• Price trend: Prices are up 1.94% year-over-year.
• Owners rate it 4.4/5 — a solid satisfaction signal.
• The 2021 adds the Nightshade Special Edition and keeps the Sequoia’s standard V8, easy-to-use tech, and full safety suite.

Consider the 2022 if:

• It keeps the same basic formula but adds a slightly updated trim lineup and continues the truck-based approach.

The bottom line: If you want the current-generation Sequoia and find a clean, fairly priced example, the 2021 is a reasonable buy. If you’re shopping mainly on price, a later-year alternative may be worth comparing, but the 2021 still makes sense for buyers who value space, V8 power, and straightforward usability.

How does the 2021 Toyota Sequoia compare to the 2021 Ford Expedition?

Expert Pros & Cons (per CarGurus review team)

2021 Toyota Sequoia:

• Pros: Powerful engine, Comfortable, Easy-to-use technology.
• Cons: Poor fuel economy, Poor handling, Poor value for money.

2021 Ford Expedition:

• Pros: Comfortable, Spacious, Powerful engine.
• Cons: Advanced safety features are not standard, Poor fuel economy.

Our experts score the 2021 Toyota Sequoia 7/10 and the 2021 Ford Expedition 7/10. The Sequoia leans harder into simplicity and easy-to-use technology, while the Expedition brings more space and a stronger overall family-hauler reputation. Both have poor fuel economy, but the Expedition’s advanced safety features are not standard, which may matter if you want more equipment without moving up trims.

Read our full side-by-side expert comparison here.

These recommendations are based on CarGurus' proprietary market data from November 10, 2026, CarGurus experts' opinions, and generative AI.