Used 2022 Lexus RX for SaleNationwide
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 45,524
- Stock #:
- N1Y0004
- VIN:
- 2T2AZMDA6NC316306
2022 Lexus RX
350 AWD
45,524 mi
$39,968
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Gray (Graphite)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 40,763
- Stock #:
- PC003580
- VIN:
- 2T2BAMCA6PC003580
2023 Lexus RX
350 F Sport Handling AWD
40,763 mi
$45,970
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Ultra White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Circuit Red
- Transmission:
- Automatic
- Mileage:
- 65,065
- Stock #:
- T19557A
- VIN:
- 2T2YZMDA3MC274920
2021 Lexus RX
350 F Sport Handling AWD
65,065 mi
$37,071
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Ultra White
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Transmission:
- 8-Speed Automatic
- Mileage:
- 58,309
- Stock #:
- 9032624A
- VIN:
- 2T2BAMCA2PC006394
2023 Lexus RX
350 F Sport Handling AWD
58,309 mi
$47,443
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 48,940
- Stock #:
- CNC228822
- VIN:
- 2T2HZMAA7NC228822
2022 Lexus RX
350 FWD
48,940 mi
$37,722
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 44,956
- Stock #:
- MC19892A
- VIN:
- 2T2HZMAA5MC198928
-$1,000
2021 Lexus RX
350 FWD
44,956 mi
$37,642
$36,642
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 63,181
- Stock #:
- 4MC199635
- VIN:
- 2T2AZMAA4MC199635
-$2,363
2021 Lexus RX
350 FWD
63,181 mi
$34,798
$33,545
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Iridium
- Combined gas mileage:
- 24 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 32,055
- Stock #:
- KC10447B
- VIN:
- 2T2BAMCAXPC031379
2023 Lexus RX
350 Premium AWD
32,055 mi
$47,065
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 46,565
- Stock #:
- 9063464A
- VIN:
- 2T2HZMAA9MC209185
2021 Lexus RX
350 FWD
46,565 mi
$35,333
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Eminent White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 64,280
- Stock #:
- MC190188
- VIN:
- 2T2AZMAA4MC190188
-$1,000
2021 Lexus RX
350 FWD
64,280 mi
$33,991
$32,991
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Nightfall Mica
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 97,062
- Stock #:
- 260296A
- VIN:
- 2T2HZMAAXNC248398
2022 Lexus RX
350 FWD
97,062 mi
$32,242
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,490
- Stock #:
- SA76747B
- VIN:
- 2T2HZMAA4MC187676
2021 Lexus RX
350 FWD
85,490 mi
$30,697
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Atomic Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 35,146
- Stock #:
- 28133
- VIN:
- 2T2AZMAA1NC247819
2022 Lexus RX
350 FWD
35,146 mi
$37,999
CarGurus Analysis:
2022 Lexus RX
With 2,477 currently listed for sale and an average price of $40,042.00, 35.3% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.77 / 5 stars and CarGurus experts gave it a 7.33 / 10.
84.6% of 2022 RX models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 37,285
- Stock #:
- A242302
- VIN:
- 2T2HZMAA7NC242302
2022 Lexus RX
350 FWD
37,285 mi
$39,024
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Birch
- Transmission:
- 8-Speed Automatic
- Mileage:
- 36,428
- Stock #:
- G041796A
- VIN:
- 2T2HZMAA4NC231662
2022 Lexus RX
350 FWD
36,428 mi
$40,377
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 96,272
- Stock #:
- 190308T
- VIN:
- 2T2HZMAA1MC190308
2021 Lexus RX
350 FWD
96,272 mi
$28,998
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- White (Parchment)
- Transmission:
- 8-Speed Automatic
- Mileage:
- 85,106
- Stock #:
- B261791A
- VIN:
- JTJHZKEA3M2018943
2021 Lexus RX
350L FWD
85,106 mi
$32,523
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Gray
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 85,902
- Stock #:
- B012899A
- VIN:
- 2T2YZMDA9NC333910
-$758
2022 Lexus RX
350 F Sport Handling AWD
85,902 mi
$34,690
$33,932
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 74,939
- Stock #:
- W159299A
- VIN:
- 2T2YZMDA7NC311503
2022 Lexus RX
350 F Sport Handling AWD
74,939 mi
$36,551
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Black
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Red
- Transmission:
- 8-Speed Automatic
- Mileage:
- 67,761
- Stock #:
- U10050
- VIN:
- 2T2YZMDA9NC365224
2022 Lexus RX
350 F Sport Handling AWD
67,761 mi
$37,774
- Year:
- 2022
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 290 hp 3.5L V6
- Exterior color:
- White Pearl
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 8-Speed Automatic
- Mileage:
- 81,908
- Stock #:
- T024688A
- VIN:
- JTJHZKEA8N2024688
2022 Lexus RX
350L FWD
81,908 mi
$34,783
- Year:
- 2023
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 275 hp 2.4L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 15,170
- Stock #:
- H460123A
- VIN:
- 2T2BAMBA9PC016129
2023 Lexus RX
350 Luxury FWD
15,170 mi
$49,594
- Year:
- 2021
- Make:
- Lexus
- Model:
- RX
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- Front-Wheel Drive
- Engine:
- 295 hp 3.5L V6
- Exterior color:
- Silver
- Combined gas mileage:
- 23 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 69,289
- Stock #:
- CMC188349
- VIN:
- 2T2HZMAA5MC188349
2021 Lexus RX
350 FWD
69,289 mi
$33,496
CarGurus Analysis: 2022 Lexus RX
overall
Summary
With 2,477 currently listed for sale and an average price of $40,042.00, 35.3% of 2022 Lexus RXs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Lexus RX 4.77 / 5 stars and CarGurus experts gave it a 7.33 / 10.
84.6% of 2022 RX models on CarGurus are accident free.
Why it stands out
The 2022 Lexus RX stands out as a luxury SUV that leans more toward comfort and refinement than outright performance. Its appeal comes from an attractive design, luxury amenities, driving comfort, and a reputation for tried-and-true reliability. It is also described as a carryover for 2022, with only minimal changes that include new colors and a standalone fog lamps option.
On the road, the RX’s strengths are its great ride quality and standard advanced safety features. That makes it an easy vehicle to recommend for buyers who value a smooth, relaxed driving experience and a well-equipped feel. At the same time, it is not the best choice for shoppers who want strong acceleration, since its performance is described as limited, and its design may be polarizing. The cabin’s ergonomic layout is also noted as a drawback, even though owners often praise the comfort, tech features, luxurious interior, and quiet cabin.
Other model years to consider
- Average price: $46,737.00
- Good/great deal percentage: 35.7%
- User rating: 5 / 5
- Total listings: 3,328
- Average price: $50,072.00
- Good/great deal percentage: 35.7%
- User rating: 5 / 5
- Total listings: 3,249
- Average price: $33,583.00
- Good/great deal percentage: 36.0%
- User rating: 4.88 / 5
- Total listings: 1,293
This analysis is based on CarGurus' proprietary market data from August 10, 2026, CarGurus experts' opinions, and generative AI.
4.8 Overall rating
Filter by rating
Marc G
Reviewed a 2022 Lexus RX on Dec 29, 2025
Good and reliable vehicle. Luxury is the cornerstone of this SUV.
Larry M
Reviewed a 2022 Lexus RX on Jul 24, 2026
I currently own a Lexus RX350. It’s been a reliable vehicle with a great quiet ride. I am looking at a newer RX350 at the current time
Terry C
Reviewed a 2022 Lexus RX on Apr 12, 2025
Non turbo Toyota reliability and smoothness and composure of a S class.
Uday T
Reviewed a 2022 Lexus RX on Jun 6, 2023
Great car, drives smooth. Lacks pick up power for a V6
2022 Lexus RX Trims
| Trim type | MSRP |
|---|---|
| 350L Luxury AWD | $56,150 |
| 350L Luxury FWD | $54,750 |
| 350 F Sport AWD | $50,800 |
| 350L FWD | $48,750 |
| 350L AWD | $50,150 |
| 350 F Sport Handling AWD | $53,200 |
| 350 AWD | $47,320 |
| 350 FWD | $45,920 |
2022 Lexus RX Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Lexus RX prices has changed over time.
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