Used 2022 Mercedes-Benz E-Class E 350 4MATIC for SaleNationwide
42 vehicles found
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,172
- Stock #:
- K3549
- VIN:
- W1KZF8EB5NB011561
2022 Mercedes-Benz E-Class
E 350 4MATIC
34,172 mi
Watertown, CT
Great Deal
$32,841
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Blue
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,858
- Stock #:
- P2085
- VIN:
- W1KZF8EB3NB074626
Price drop
-$799
2022 Mercedes-Benz E-Class
E 350 4MATIC
34,858 mi
Mount Holly, NJ
Good Deal
$34,494
$33,695
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 59,878
- Stock #:
- JG2013PB
- VIN:
- W1KZF8EB4NB059245
2022 Mercedes-Benz E-Class
E 350 4MATIC
59,878 mi
Ashland, VA
Fair Deal
$32,995
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,412
- Stock #:
- 3081179C
- VIN:
- W1KZF8EB9NB058463
2022 Mercedes-Benz E-Class
E 350 4MATIC
64,412 mi
Franklin, TN
Fair Deal
$31,962
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 25,311
- Stock #:
- M1148
- VIN:
- W1KZF8EB6NB031222
2022 Mercedes-Benz E-Class
E 350 4MATIC
25,311 mi
Green Brook, NJ
Fair Deal
$37,033
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,783
- Stock #:
- 021571
- VIN:
- W1KZF8EB3NB021571
2022 Mercedes-Benz E-Class
E 350 4MATIC
47,783 mi
Sandy Springs, GA
Good Deal
$33,083
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,795
- Stock #:
- V4034
- VIN:
- W1KZF8EB1NB055654
2022 Mercedes-Benz E-Class
E 350 4MATIC
47,795 mi
Huntley, IL
Great Deal
$31,853
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Graphite Gray Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Deep White/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 56,785
- Stock #:
- NB034405
- VIN:
- W1KZF8EB7NB034405
2022 Mercedes-Benz E-Class
E 350 4MATIC
56,785 mi
Tulsa, OK
Great Deal
$29,808
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,601
- Stock #:
- 20401MK2
- VIN:
- W1KZF8EB4NB015584
2022 Mercedes-Benz E-Class
E 350 4MATIC
23,601 mi
North Haven, CT
Good Deal
$38,149
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Deep White/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 34,634
- Stock #:
- NB008480
- VIN:
- W1KZF8EB1NB008480
2022 Mercedes-Benz E-Class
E 350 4MATIC
34,634 mi
Duluth, GA
Good Deal
$35,688
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Cirrus Silver
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Neva Gray/Magma Gray
- Transmission:
- 9-Speed Automatic
- Mileage:
- 26,839
- Stock #:
- NP029840P
- VIN:
- W1KZF8EB0NB029840
2022 Mercedes-Benz E-Class
E 350 4MATIC
26,839 mi
West Chester, PA
Fair Deal
$37,471
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 23,067
- Stock #:
- NB024054
- VIN:
- W1KZF8EB9NB024054
2022 Mercedes-Benz E-Class
E 350 4MATIC
23,067 mi
Springfield, MO
Fair Deal
$38,478
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 9,526
- Stock #:
- 072952
- VIN:
- W1KZF8EB6NB072952
2022 Mercedes-Benz E-Class
E 350 4MATIC
9,526 mi
Sykesville, MD
Good Deal
$40,294
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Grey)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,147
- Stock #:
- 66142
- VIN:
- W1KZF8EB0NB071120
2022 Mercedes-Benz E-Class
E 350 4MATIC
38,147 mi
Wall Township, NJ
Fair Deal
$33,294
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Nautical Blue Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 48,674
- Stock #:
- NB032117A
- VIN:
- W1KZF8EB3NB032117
2022 Mercedes-Benz E-Class
E 350 4MATIC
48,674 mi
San Antonio, TX
Fair Deal
$33,887
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 80,909
- Stock #:
- M4109A
- VIN:
- W1KZF8EB1NB071255
Price drop
-$2,349
2022 Mercedes-Benz E-Class
E 350 4MATIC
80,909 mi
Wilmington, NC
Good Deal
$30,248
$28,748
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 22,677
- Stock #:
- 30903
- VIN:
- W1KZF8EB7NB044531
2022 Mercedes-Benz E-Class
E 350 4MATIC
22,677 mi
Yonkers, NY
Great Deal
$33,460
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White - 149
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Grey - 105)
- Transmission:
- Automatic
- Mileage:
- 67,460
- Stock #:
- A2607159
- VIN:
- W1KZF8EB4NB006982
2022 Mercedes-Benz E-Class
E 350 4MATIC
67,460 mi
Allentown, PA
Good Deal
$28,390
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Black
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 14,443
- Stock #:
- TNB023244
- VIN:
- W1KZF8EB9NB023244
New arrival
2022 Mercedes-Benz E-Class
E 350 4MATIC
14,443 mi
Denver, CO
Fair Deal
$38,999
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 27,555
- Stock #:
- 018881T
- VIN:
- W1KZF8EB3NB018881
Price drop
-$1,100
2022 Mercedes-Benz E-Class
E 350 4MATIC
27,555 mi
Honesdale, PA
Fair Deal
$37,485
$36,385
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Tan)
- Transmission:
- Automatic
- Mileage:
- 76,452
- Stock #:
- TU3065
- VIN:
- W1KZF8EB8NB029908
2022 Mercedes-Benz E-Class
E 350 4MATIC
76,452 mi
New Hyde Park, NY
Great Deal
$24,170
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- MANUFAKTUR Macchiato Beige/Saddle Brown
- Mileage:
- 33,202
- Stock #:
- XNB032433
- VIN:
- W1KZF8EB2NB032433
New arrival
2022 Mercedes-Benz E-Class
E 350 4MATIC
33,202 mi
Georgetown, TX
Good Deal
$35,014
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Wy
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Magma Gray)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 39,632
- Stock #:
- U36044
- VIN:
- W1KZF8EB8NB033151
2022 Mercedes-Benz E-Class
E 350 4MATIC
39,632 mi
Patchogue, NY
Fair Deal
$35,115
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- E-Class
- Body type:
- Sedan
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 255 hp 2L I4
- Exterior color:
- Polar White
- Combined gas mileage:
- 25 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 38,844
- Stock #:
- 5735
- VIN:
- W1KZF8EB6NB020155
Photos coming soon
New arrival
2022 Mercedes-Benz E-Class
E 350 4MATIC
38,844 mi
Warren, MI
Fair Deal
$35,270
FAQs
How much does the Mercedes-Benz E-Class E 350 4MATIC cost?
The average Mercedes-Benz E-Class E 350 4MATIC costs about $39,807.05. The average price has decreased by -2.1% since last year. The 930 for sale on CarGurus range from $2,050 to $80,418 in price.
How many Mercedes-Benz E-Class E 350 4MATIC vehicles have no reported accidents or damage?
753 out of 930 for sale have no reported accidents or damage.
What is the fuel economy of the Mercedes-Benz E-Class E 350 4MATIC?
Depending on the engine and options, the Mercedes-Benz E-Class E 350 4MATIC gets between 18 and 28 MPG/MPGe.
What fuel types are available?
Gasoline engines are available.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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