Used 2022 Mercedes-Benz GLS for Sale nearPittsburgh, PA
Shop with transparent pricing.
Only show listings that include dealer fees- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,597
- Stock #:
- LP2836A
- VIN:
- 4JGFF5KE0MA489803

Sponsored Listing
2021 Mercedes-Benz GLS
450 4MATIC
36,597 mi
$41,456
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 35,395
- Stock #:
- X947120
- VIN:
- 4JGFF8KE9PA947120

2023 Mercedes-Benz GLS
AMG GLS 63 4MATIC
35,395 mi
$81,958
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 21,140
- Stock #:
- 25837B
- VIN:
- 4JGFF5KE1NA762393

2022 Mercedes-Benz GLS
450 4MATIC
21,140 mi
$52,544
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Mojave Silver Metallic
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 36,597
- Stock #:
- LP2836A
- VIN:
- 4JGFF5KE0MA489803

2021 Mercedes-Benz GLS
450 4MATIC
36,597 mi
$41,456
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 30,043
- Stock #:
- 944834
- VIN:
- 4JGFF5KE2PA944834

-$1,600
2023 Mercedes-Benz GLS
450 4MATIC
30,043 mi
$58,947
$57,347
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 49,606
- Stock #:
- LR629520A
- VIN:
- 4JGFF5KE3NA694372

-$1,000
2022 Mercedes-Benz GLS
450 4MATIC
49,606 mi
$45,692
$44,692
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 550 hp 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 17 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- Automatic
- Mileage:
- 58,325
- Stock #:
- 861008
- VIN:
- 4JGFF8HB5PA861008

2023 Mercedes-Benz GLS
600 Mercedes-Maybach 4MATIC
58,325 mi
$91,092
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Black
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- 9-Speed Automatic
- Mileage:
- 30,015
- Stock #:
- 004717
- VIN:
- 4JGFF8GE4PB004717

2023 Mercedes-Benz GLS
580 4MATIC
30,015 mi
$64,780
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Obsidian Black
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 11,946
- Stock #:
- PM7168
- VIN:
- 4JGFF5KE0PA931905

2023 Mercedes-Benz GLS
450 4MATIC
11,946 mi
$58,396
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Gray (Selenite Grey Metallic)
- Combined gas mileage:
- 20 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 33,984
- Stock #:
- 65860
- VIN:
- 4JGFF5KE7PA880435

2023 Mercedes-Benz GLS
450 4MATIC
33,984 mi
$51,347
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- White
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 60,278
- Stock #:
- 824083
- VIN:
- 4JGFF5KE1NA824083

2022 Mercedes-Benz GLS
450 4MATIC
60,278 mi
$42,484
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Espresso Brown/Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,225
- Stock #:
- D2126A
- VIN:
- 4JGFF5KE4NA664359

2022 Mercedes-Benz GLS
450 4MATIC
64,225 mi
$45,358
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Selenite Gray Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 64,319
- Stock #:
- 305698LT
- VIN:
- 4JGFF8KE7MA305698

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
64,319 mi
$61,058
CarGurus Analysis:
2022 Mercedes-Benz GLS
With 170 currently listed for sale near Pittsburgh, PA and an average price of $39,194, 31.8% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
80.6% of 2022 GLS models on CarGurus are accident free.
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Cirrus Silver Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 87,802
- Stock #:
- HP1291
- VIN:
- 4JGFF5KE5NA648574

2022 Mercedes-Benz GLS
450 4MATIC
87,802 mi
$35,987
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Black
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 44,654
- Stock #:
- E2663A
- VIN:
- 4JGFF5KE7NA630724

2022 Mercedes-Benz GLS
450 4MATIC
44,654 mi
$43,539
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Polar White
- Combined gas mileage:
- 22 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 93,744
- Stock #:
- AW260157A
- VIN:
- 4JGFF5KEXMA442083

2021 Mercedes-Benz GLS
450 4MATIC
93,744 mi
$30,774
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- Green
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Transmission:
- Automatic
- Mileage:
- 76,548
- Stock #:
- 382075
- VIN:
- 4JGFF8GE3MA382075

2021 Mercedes-Benz GLS
580 4MATIC
76,548 mi
$42,181
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 4L V8
- Exterior color:
- designo Diamond White Bright
- Combined gas mileage:
- 18 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Mahagony/Macchiato Beige)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 58,531
- Stock #:
- 384920
- VIN:
- 4JGFF8GE2MA384920

2021 Mercedes-Benz GLS
580 4MATIC
58,531 mi
$47,450
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Red
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black
- Transmission:
- 9-Speed Automatic
- Mileage:
- 61,380
- Stock #:
- 605846
- VIN:
- 4JGFF5KE6NA605846

2022 Mercedes-Benz GLS
450 4MATIC
61,380 mi
$41,650
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic - 890
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Black - 111
- Transmission:
- Automatic
- Mileage:
- 29,611
- Stock #:
- UC5027A
- VIN:
- 4JGFF5KE5NA580809

2022 Mercedes-Benz GLS
450 4MATIC
29,611 mi
$50,846
- Year:
- 2023
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- White
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown
- Transmission:
- 9-Speed Automatic
- Mileage:
- 42,880
- Stock #:
- 7497
- VIN:
- 4JGFF8KEXPA966128

2023 Mercedes-Benz GLS
AMG GLS 63 4MATIC
42,880 mi
$81,893
- Year:
- 2022
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 362 hp 3L I6
- Exterior color:
- Lunar Blue Metallic
- Combined gas mileage:
- 21 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 31,199
- Stock #:
- SP768279
- VIN:
- 4JGFF5KE0NA768279

2022 Mercedes-Benz GLS
450 4MATIC
31,199 mi
$49,483
- Year:
- 2021
- Make:
- Mercedes-Benz
- Model:
- GLS
- Body type:
- SUV / Crossover
- Doors:
- 4 doors
- Drivetrain:
- All-Wheel Drive
- Engine:
- 603 hp 4L V8
- Exterior color:
- Iridium Silver Metallic
- Combined gas mileage:
- 16 MPG
- Fuel type:
- Gasoline
- Interior color:
- Brown (Macchiato Beige/Black)
- Transmission:
- 9-Speed Automatic
- Mileage:
- 47,602
- Stock #:
- 64252
- VIN:
- 4JGFF8KE5MA357220

2021 Mercedes-Benz GLS
AMG GLS 63 4MATIC AWD
47,602 mi
$66,847
CarGurus Analysis: 2022 Mercedes-Benz GLS
overall

Summary
With 170 currently listed for sale near Pittsburgh, PA and an average price of $39,194, 31.8% of 2022 Mercedes-Benz GLSs for sale on CarGurus are rated as good or great deals.
Favorably reviewed: Owners rated the 2022 Mercedes-Benz GLS 5 / 5 stars and CarGurus experts gave it a 7.33 / 10.
80.6% of 2022 GLS models on CarGurus are accident free.
Why it stands out
The 2022 Mercedes-Benz GLS sits at the top of Mercedes’ luxury SUV range and is the brand’s biggest SUV. Its “S” designation signals that it is meant to be the SUV equivalent of Mercedes’ flagship S-Class sedan, which helps explain why the GLS is positioned as a full-size luxury statement rather than just a practical family hauler. Mercedes also says the flagship SUV is big on both luxury and utility, and that combination is central to its appeal.
For 2022, Mercedes withdrew most of its V8 models from the United States, leaving only the base six-cylinder GLS 450 4Matic model. That makes this version of the GLS notable for being the only one available at the time of testing, and it still brings the strengths highlighted in the test drive data: stylish design, a powerful engine, and a spacious cabin. Those qualities make it easy to see why buyers would be drawn to it if they want a large, upscale SUV with a strong presence and plenty of room.
The tradeoffs are just as important. The test drive data points to poor ride quality, advanced safety features that are not standard, and poor ergonomic design. So while the 2022 Mercedes-Benz GLS stands out for luxury, size, and utility, it also asks buyers to accept some comfort and usability compromises.
Other model years to consider
- Average price: $94,155
- Good/great deal percentage: 29.6%
- User rating: 5 / 5
- Total listings: 216
- Average price: $30,314
- Good/great deal percentage: 34.3%
- User rating: 5 / 5
- Total listings: 175
- Average price: $89,000
- Good/great deal percentage: 28.4%
- Total listings: 204
This analysis is based on CarGurus' proprietary market data from September 8, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
5.0 Overall rating
Filter by rating
rick j
Reviewed a 2022 Mercedes-Benz AMG GLS 63 4MATIC on Aug 23, 2022
This is an amazing vehicle. It has comfort and class plus power. Love it!
Robert S
Reviewed a 2022 Mercedes-Benz GLS on Jun 7, 2022
Major improvement over prior models … driver assist substantially better
Jim A
Reviewed a 2022 Mercedes-Benz GLS on Jul 20, 2023
Cool looking, Mercedes quality, spacious, comfortable, excellent performance and dependable.
2022 Mercedes-Benz GLS Trims
| Trim type | MSRP |
|---|---|
| 580 4MATIC | $101,250 |
| AMG GLS 63 4MATIC | $135,400 |
| 450 4MATIC | $77,850 |
| 600 Mercedes-Maybach 4MATIC | $165,100 |
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
2022 Mercedes-Benz GLS Price Trends
CarGurus tracks the prices of millions of used car listings every year. See how the average price of 2022 Mercedes-Benz GLS prices has changed over time.
See more price trends2022 Mercedes-Benz GLS Pricing Analysis: Pittsburgh, PA Market Report
Pricing by Nearby Locations
Market Area: Pittsburgh, PA
Key Insights
- Highest Prices in Youngstown: The market in Youngstown, OH ($103,748) reflects a premium pricing strategy, likely due to limited inventory and high demand for luxury vehicles.
- Stable Pricing in Greensburg and Boyers: Both Greensburg and Boyers show consistent pricing at $35,987, indicating a balanced supply and demand in these areas.
- Inventory Levels: The Akron, OH market has a similar average price to Youngstown but with a slightly higher inventory (177 listings), suggesting a potential for price competition.
City-Level Pricing
| City | Total Listings | Avg Price |
|---|---|---|
| Youngstown, OH | 175 | $103,748 |
| Akron, OH | 177 | $103,748 |
| Greensburg, PA | 173 | $35,987 |
| Boyers, PA | 164 | $35,987 |
Pricing by Trim Packages
Key Insights
- Most Common Trim: The 450 4MATIC is the most prevalent trim with 402 listings, indicating strong demand for this model.
- Price Range Across Trims: The AMG GLS 63 4MATIC commands the highest MSRP at $135,400, reflecting its luxury features and performance capabilities.
- AWD Popularity: All trims are AWD, catering to consumer preferences for all-weather capability, which is likely driving higher inventory levels for these models.
Trim-Level Details
| Trim | Listings | MSRP | Drivetrain | Engine |
|---|---|---|---|---|
| 450 4MATIC | 402 | $77,850 | AWD | 3.0L 362 hp I6 |
| 580 4MATIC | 52 | $101,250 | AWD | 4.0L 483 hp V8 |
| AMG GLS 63 4MATIC | 67 | $135,400 | AWD | 4.0L 603 hp V8 |
| 600 Mercedes-Maybach 4MATIC | 67 | $165,100 | AWD | 4.0L 550 hp V8 |
Pricing Analysis by Model Year
Key Insights
- New Models at a Premium: The 2026 model is priced at $84,186, which is about -6.5% below MSRP, indicating a slight depreciation trend for the newest models.
- Significant Depreciation for Older Models: The 2017 model shows a steep decline, priced at $14,995, reflecting a -77.7% depreciation from its original MSRP.
- Best Value in Recent Years: The 2021 model offers a balance of price and features, currently averaging $35,870, which is -52.8% below MSRP, making it an attractive option for buyers.
Model Year Pricing
| Model Year | Original MSRP | Avg Price | Price vs MSRP |
|---|---|---|---|
| 2026 Mercedes-Benz GLS | $90,250 | $84,186 | -6.5% |
| 2025 Mercedes-Benz GLS | $89,200 | $77,998 | -12.5% |
| 2024 Mercedes-Benz GLS | $87,000 | $93,295 | +7.2% |
| 2021 Mercedes-Benz GLS | $76,000 | $35,870 | -52.8% |
| 2020 Mercedes-Benz GLS | $75,200 | $30,269 | -59.8% |
| 2019 Mercedes-Benz GLS | $70,150 | $20,951 | -70.2% |
| 2017 Mercedes-Benz GLS | $67,050 | $14,995 | -77.7% |
These recommendations are based on CarGurus' proprietary market data from September 10, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
How much does the 2022 Mercedes-Benz GLS cost?
| Metric | Value |
|---|---|
| Current Average Price | $47,864 |
| Year-Round Low | $47,864 |
| Year-Round High | $55,920 |
| Average Price a Year Ago | $55,924 |
| Change vs. Last Year | −14.41% |
Prices have softened 14.41% compared to this time last year, making it a favorable time to shop this model year.
There are 860 listings available, which gives you a decent amount of inventory to compare.
Is the 2022 Mercedes-Benz GLS a good car?
Yes — the 2022 Mercedes-Benz GLS earns a 5/5 user rating and a 7.33/10 expert rating. The standout strength is Look and feel at 9/10.
It sits at the top of Mercedes’ luxury SUV range and is positioned as the brand’s flagship three-row SUV, so you’re shopping for a full-size luxury statement rather than a simple family hauler. The test-drive data backs that up with a stylish design, a powerful engine, and a spacious cabin.
The trade-offs are worth weighing: poor ride quality and poor ergonomic design are both called out, and advanced safety features are not standard. For you, that means the GLS makes the most sense if you value luxury presence and space more than outright comfort polish or a fully loaded standard feature set.
34.7% of listings are priced as good or great deals, which suggests there are still some attractive opportunities if you shop carefully.
Is the 2022 Mercedes-Benz GLS reliable?
Owners rate it 5/5, a strong signal of long-term satisfaction.
The GLS is described as a luxury SUV with a strong emphasis on comfort, upscale presentation, and everyday usefulness, and the expert review also highlights its spacious cabin and strong performance. Its 3.0-liter turbocharged inline-six with EQ Boost is presented as smooth and well suited to a luxury vehicle, and the mild-hybrid setup helps the engine work more efficiently.
Mercedes also notes that the electric motor powers most accessories, reducing the engine’s workload, and the standard air suspension can raise and lower ride height. On the ownership side, Mercedes includes a four-year, 50,000-mile basic warranty and a four-year, 50,000-mile powertrain warranty.
For a used buyer, the main long-term risk is that a large, complex luxury SUV can be expensive to keep in top shape if prior maintenance was neglected.
What should I look for when buying a used 2022 Mercedes-Benz GLS?
Accident-free inventory is solid at 87.1% — always verify the vehicle history report.
You should still run a history report on any candidate and prioritize a pre-purchase inspection, especially on a large luxury SUV with available options and complex systems. Focus on how the cabin, suspension, and electronics have aged, since comfort and usability are central to the GLS experience.
Key things to evaluate:
- Trim level: The base GLS 450 form is more subtle and less flashy than the higher-performance and ultra-luxury versions, and the test car’s fairly basic interior lacked reclining seats. That means you should pay close attention to whether the equipment level matches your expectations for a flagship SUV.
- Powertrain: The GLS 450 uses a 3.0-liter turbocharged inline-six with a nine-speed automatic and EQ Boost mild-hybrid assistance. It makes 362 horsepower and 369 pound-feet of torque, with an electric motor that can add 21 hp and 184 lb-ft in short bursts.
- Safety package: Standard equipment includes forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Adaptive cruise control, lane-keep assist, second-row side airbags, and more advanced driver-assistance features cost extra.
- Infotainment: The standard MBUX system includes a 12.3-inch touchscreen, a 12.3-inch digital instrument cluster, Bluetooth, Apple CarPlay/Android Auto, navigation, SiriusXM satellite radio, and natural-language voice recognition. A 13-speaker Burmester audio system is standard, while a head-up display is optional.
- Fuel efficiency: EPA ratings are 20 mpg combined, 18 mpg city, and 24 mpg highway.
Which 2022 Mercedes-Benz GLS trim should I buy?
The 2022 Mercedes-Benz GLS is offered in 1 trim level: GLS 450 4Matic.
Here's the short version:
The GLS 450 4Matic is the only version available for this model year, so your decision is really about whether the standard equipment and luxury character fit your needs. It brings the smooth inline-six powertrain, standard AWD, air suspension, and a strong tech package, which makes it the clear choice if you want the GLS experience without waiting for a higher-output variant to return.
Mercedes’ safety content also notes that several advanced driver-assistance features are optional, so you should check carefully for the equipment you want before buying.
Is now a good time to buy a used 2022 Mercedes-Benz GLS?
This looks like a moderate, selective buyer’s market, so you can shop with some leverage if you’re patient.
- Deal availability: 34.7% of listings are priced as good or great deals.
- Inventory: There are 860 listings available.
- Price trend: Prices have softened 14.41% compared with last year.
- Clean inventory: 87.1% of listings are accident-free.
If you find a listing below $47,864, that's toward the low end of the year-round range and worth acting on quickly.
What is the 2022 Mercedes-Benz GLS's resale value?
The current average of $47,864 sits slightly below last year's $55,924.
That price drop suggests the market has already adjusted downward, which can help you buy at a more favorable point in the cycle. If you plan to sell later, the current softness means your future resale will depend heavily on condition, mileage, and how well the vehicle has been maintained.
Because this model year still carries strong demand signals from shoppers looking for a large luxury SUV, a clean example should remain easier to move than a neglected one. Vehicles with strong owner satisfaction ratings, like this model year's 5/5, tend to retain buyer demand, which supports resale value over time.
Is the 2022 Mercedes-Benz GLS safe?
It earns a 6/10 safety score from our experts.
Standard safety features include forward collision warning, automatic emergency braking, a driver-attention monitor, automatic high beams, blind-spot monitoring, a surround-view camera system, Crosswind Assist, parking assist, and Pre Safe. Mercedes also says the audio system emits pink noise intended to help protect ears during a collision.
You should note that adaptive cruise control, lane-keep assist, second-row side airbags, and several more advanced driver-assistance features are not standard. That means you’ll want to verify exactly which safety equipment is installed on any used example you’re considering.
Should I buy a 2022 Mercedes-Benz GLS or consider a different year?
If you're weighing the 2022 against nearby model years, here's how to think about it:
Choose the 2022 if:
- 34.7% of listings are priced as good or great deals.
- Accident-free inventory is solid at 87.1% — always verify the vehicle history report.
- Price trend: Prices have softened 14.41% compared with last year.
- Owners rate it 5/5 — a strong satisfaction signal.
- The 2022 is notable for being the only GLS version available at the time of testing, with a smooth inline-six and standard AWD.
Consider the 2021 if:
- At $47,956, the 2021 costs more than the current year's $47,864 average.
- It emphasizes comfort and upscale presentation with three rows of spacious seating.
The bottom line: If you want the best mix of current pricing, inventory, and the specific 2022 setup, this is the year to target. If you’re mainly comparing on price, the 2021 doesn’t offer a clear savings advantage here, so you’re usually better off focusing on the cleaner, better-priced 2022 listings.
These recommendations are based on CarGurus' proprietary market data from September 11, 2026, CarGurus experts' opinions, and generative AI.
*CarGurus meticulously monitors the prices of millions of pre-owned vehicle listings, offering users precise and up-to-date market insights. Historical pricing data excludes any additional dealer fees as of May 3, 2026.
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